Synergistic Effects of Pulsed Lavage and Antimicrobial Therapy Against Staphylococcus aureus Biofilms in an in-vitro Model

Synergistic Effects of Pulsed Lavage and Antimicrobial Therapy Against Staphylococcus aureus Biofilms in an in-vitro Model

Background: Prosthetic joint infections (PJI) are difficult to treat complications of joint arthroplasty. Debridement with implant retention is a common treatment strategy and frequently involves the use of pulsed lavage (PL). However, PL effects on biofilms and antibiotic activity have been scarcel...

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Bibliographic Details
Main Authors: Hervé Poilvache, Albert Ruiz-Sorribas, George Sakoulas, Hector Rodriguez-Villalobos, Olivier Cornu, Françoise Van Bambeke
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Medicine
Subjects:
biofilm
MRSA
MSSA
pulsed lavage
vancomycin
flucloxacillin
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.00527/full

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