Management of Non-Culprit Lesions in STEMI Patients with Multivessel Disease
Multivessel disease is observed in approximately 50% of patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). Data from randomized clinical trials has shown that complete revascularization in the STEMI setting improves clinical...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-03-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/7/2572 |
| _version_ | 1797607633442570240 |
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| author | Raffaele Piccolo Lina Manzi Fiorenzo Simonetti Attilio Leone Domenico Angellotti Maddalena Immobile Molaro Nicola Verde Plinio Cirillo Luigi Di Serafino Anna Franzone Carmen Anna Maria Spaccarotella Giovanni Esposito |
| author_facet | Raffaele Piccolo Lina Manzi Fiorenzo Simonetti Attilio Leone Domenico Angellotti Maddalena Immobile Molaro Nicola Verde Plinio Cirillo Luigi Di Serafino Anna Franzone Carmen Anna Maria Spaccarotella Giovanni Esposito |
| author_sort | Raffaele Piccolo |
| collection | DOAJ |
| description | Multivessel disease is observed in approximately 50% of patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). Data from randomized clinical trials has shown that complete revascularization in the STEMI setting improves clinical outcomes by reducing the risk of reinfarction and urgent revascularization. However, the timing and modality of revascularization of non-culprit lesions are still debated. PCI of non-culprit lesions can be performed during the index primary PCI or as a staged procedure and can be guided by angiography, functional assessment, or intracoronary imaging. In this review, we summarize the available evidence about the management of non-culprit lesions in STEMI patients with or without cardiogenic shock. |
| first_indexed | 2024-03-11T05:32:36Z |
| format | Article |
| id | doaj.art-336526c6194e427cac74d3956c654444 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T05:32:36Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-336526c6194e427cac74d3956c6544442023-11-17T16:58:57ZengMDPI AGJournal of Clinical Medicine2077-03832023-03-01127257210.3390/jcm12072572Management of Non-Culprit Lesions in STEMI Patients with Multivessel DiseaseRaffaele Piccolo0Lina Manzi1Fiorenzo Simonetti2Attilio Leone3Domenico Angellotti4Maddalena Immobile Molaro5Nicola Verde6Plinio Cirillo7Luigi Di Serafino8Anna Franzone9Carmen Anna Maria Spaccarotella10Giovanni Esposito11Department of Advanced Biomedical Sciences, University of Naples Federico II, 80131 Naples, ItalyDepartment of Advanced Biomedical Sciences, University of Naples Federico II, 80131 Naples, ItalyDepartment of Advanced Biomedical Sciences, University of Naples Federico II, 80131 Naples, ItalyDepartment of Advanced Biomedical Sciences, University of Naples Federico II, 80131 Naples, ItalyDepartment of Advanced Biomedical Sciences, University of Naples Federico II, 80131 Naples, ItalyDepartment of Advanced Biomedical Sciences, University of Naples Federico II, 80131 Naples, ItalyDepartment of Advanced Biomedical Sciences, University of Naples Federico II, 80131 Naples, ItalyDepartment of Advanced Biomedical Sciences, University of Naples Federico II, 80131 Naples, ItalyDepartment of Advanced Biomedical Sciences, University of Naples Federico II, 80131 Naples, ItalyDepartment of Advanced Biomedical Sciences, University of Naples Federico II, 80131 Naples, ItalyDepartment of Advanced Biomedical Sciences, University of Naples Federico II, 80131 Naples, ItalyDepartment of Advanced Biomedical Sciences, University of Naples Federico II, 80131 Naples, ItalyMultivessel disease is observed in approximately 50% of patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). Data from randomized clinical trials has shown that complete revascularization in the STEMI setting improves clinical outcomes by reducing the risk of reinfarction and urgent revascularization. However, the timing and modality of revascularization of non-culprit lesions are still debated. PCI of non-culprit lesions can be performed during the index primary PCI or as a staged procedure and can be guided by angiography, functional assessment, or intracoronary imaging. In this review, we summarize the available evidence about the management of non-culprit lesions in STEMI patients with or without cardiogenic shock.https://www.mdpi.com/2077-0383/12/7/2572non-culprit coronary lesionSTEMIcomplete revascularizationmultivessel diseaseculprit lesionmyocardial infarction |
| spellingShingle | Raffaele Piccolo Lina Manzi Fiorenzo Simonetti Attilio Leone Domenico Angellotti Maddalena Immobile Molaro Nicola Verde Plinio Cirillo Luigi Di Serafino Anna Franzone Carmen Anna Maria Spaccarotella Giovanni Esposito Management of Non-Culprit Lesions in STEMI Patients with Multivessel Disease Journal of Clinical Medicine non-culprit coronary lesion STEMI complete revascularization multivessel disease culprit lesion myocardial infarction |
| title | Management of Non-Culprit Lesions in STEMI Patients with Multivessel Disease |
| title_full | Management of Non-Culprit Lesions in STEMI Patients with Multivessel Disease |
| title_fullStr | Management of Non-Culprit Lesions in STEMI Patients with Multivessel Disease |
| title_full_unstemmed | Management of Non-Culprit Lesions in STEMI Patients with Multivessel Disease |
| title_short | Management of Non-Culprit Lesions in STEMI Patients with Multivessel Disease |
| title_sort | management of non culprit lesions in stemi patients with multivessel disease |
| topic | non-culprit coronary lesion STEMI complete revascularization multivessel disease culprit lesion myocardial infarction |
| url | https://www.mdpi.com/2077-0383/12/7/2572 |
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