Unraveling the Mechanism of Platelet Aggregation Suppression by Thioterpenoids: Molecular Docking and In Vivo Antiaggregant Activity

Unraveling the Mechanism of Platelet Aggregation Suppression by Thioterpenoids: Molecular Docking and In Vivo Antiaggregant Activity

Natural monoterpenes and their derivatives are widely considered the effective ingredients for the design and production of novel biologically active compounds. In this study, by using the molecular docking technique, we examined the effects of two series of “sulfide-sulfoxide-sulfone” thioterpenoid...

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Main Authors:	Liliya E. Nikitina, Pavel S. Bocharov, Alexander A. Ksenofontov, Elena V. Antina, Ilmir R. Gilfanov, Roman S. Pavelyev, Olga V. Ostolopovskaya, Inna V. Fedyunina, Zulfiya R. Azizova, Svetlana V. Pestova, Evgeniy S. Izmest’ev, Svetlana A. Rubtsova, Sergei V. Boichuk, Aigul R. Galembikova, Elena A. Smolyarchuk, Ilshat G. Mustafin, Airat R. Kayumov, Aleksandr V. Samorodov
Format:	Article
Language:	English
Published:	MDPI AG 2023-11-01
Series:	Biomimetics
Subjects:	<i>S</i>-containing monoterpenoids molecular docking integrin α<sub>IIb</sub>β<sub>3</sub> antiaggregant activity
Online Access:	https://www.mdpi.com/2313-7673/8/8/570

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