Sonocatalytic Optimization of Titanium‐Based Therapeutic Nanomedicine
Abstract Recent considerable technological advances in ultrasound‐based treatment modality provides a magnificent prospect for scientific communities to conquer the related diseases, which is featured with remarkable tissue penetration, non‐invasive and non‐thermal characteristics. As one of the cri...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-09-01
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| Series: | Advanced Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/advs.202301764 |
| _version_ | 1797692652544589824 |
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| author | Ruirui Zhou Meiqi Chang Mengjun Shen Yang Cong Yu Chen Yin Wang |
| author_facet | Ruirui Zhou Meiqi Chang Mengjun Shen Yang Cong Yu Chen Yin Wang |
| author_sort | Ruirui Zhou |
| collection | DOAJ |
| description | Abstract Recent considerable technological advances in ultrasound‐based treatment modality provides a magnificent prospect for scientific communities to conquer the related diseases, which is featured with remarkable tissue penetration, non‐invasive and non‐thermal characteristics. As one of the critical elements that influences treatment outcomes, titanium (Ti)‐based sonosensitizers with distinct physicochemical properties and exceptional sonodynamic efficiency have been applied extensively in the field of nanomedical applications. To date, a myriad of methodologies has been designed to manipulate the sonodynamic performance of titanium‐involved nanomedicine and further enhance the productivity of reactive oxygen species for disease treatments. In this comprehensive review, the sonocatalytic optimization of diversified Ti‐based nanoplatforms, including defect engineering, plasmon resonance modulation, heterojunction, modulating tumor microenvironment, as well as the development of synergistic therapeutic modalities is mainly focused. The state‐of‐the‐art Ti‐based nanoplatforms ranging from preparation process to the extensive medical applications are summarized and highlighted, with the goal of elaborating on future research prospects and providing a perspective on the bench‐to‐beside translation of these sonocatalytic optimization tactics. Furthermore, to spur further technological advancements in nanomedicine, the difficulties currently faced and the direction of sonocatalytic optimization of Ti‐based therapeutic nanomedicine are proposed and outlooked. |
| first_indexed | 2024-03-12T02:31:42Z |
| format | Article |
| id | doaj.art-336aad7d812848f5b69e12bcec36e186 |
| institution | Directory Open Access Journal |
| issn | 2198-3844 |
| language | English |
| last_indexed | 2024-03-12T02:31:42Z |
| publishDate | 2023-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advanced Science |
| spelling | doaj.art-336aad7d812848f5b69e12bcec36e1862023-09-05T07:49:09ZengWileyAdvanced Science2198-38442023-09-011025n/an/a10.1002/advs.202301764Sonocatalytic Optimization of Titanium‐Based Therapeutic NanomedicineRuirui Zhou0Meiqi Chang1Mengjun Shen2Yang Cong3Yu Chen4Yin Wang5Department of Ultrasound Shanghai Pulmonary Hospital School of Medicine Tongji University Shanghai 200433P. R. ChinaLaboratory Center Shanghai Municipal Hospital of Traditional Chinese Medicine Shanghai University of Traditional Chinese Medicine Shanghai 200071P. R. ChinaDepartment of Ultrasound Shanghai Pulmonary Hospital School of Medicine Tongji University Shanghai 200433P. R. ChinaDepartment of Ultrasound Shanghai Pulmonary Hospital School of Medicine Tongji University Shanghai 200433P. R. ChinaMaterdicine Lab School of Life Sciences Shanghai University Shanghai 200444P. R. ChinaDepartment of Ultrasound Shanghai Pulmonary Hospital School of Medicine Tongji University Shanghai 200433P. R. ChinaAbstract Recent considerable technological advances in ultrasound‐based treatment modality provides a magnificent prospect for scientific communities to conquer the related diseases, which is featured with remarkable tissue penetration, non‐invasive and non‐thermal characteristics. As one of the critical elements that influences treatment outcomes, titanium (Ti)‐based sonosensitizers with distinct physicochemical properties and exceptional sonodynamic efficiency have been applied extensively in the field of nanomedical applications. To date, a myriad of methodologies has been designed to manipulate the sonodynamic performance of titanium‐involved nanomedicine and further enhance the productivity of reactive oxygen species for disease treatments. In this comprehensive review, the sonocatalytic optimization of diversified Ti‐based nanoplatforms, including defect engineering, plasmon resonance modulation, heterojunction, modulating tumor microenvironment, as well as the development of synergistic therapeutic modalities is mainly focused. The state‐of‐the‐art Ti‐based nanoplatforms ranging from preparation process to the extensive medical applications are summarized and highlighted, with the goal of elaborating on future research prospects and providing a perspective on the bench‐to‐beside translation of these sonocatalytic optimization tactics. Furthermore, to spur further technological advancements in nanomedicine, the difficulties currently faced and the direction of sonocatalytic optimization of Ti‐based therapeutic nanomedicine are proposed and outlooked.https://doi.org/10.1002/advs.202301764sonocatalyticsonodynamic therapysonosensitizerstitanium‐based nanomedicineultrasound therapy |
| spellingShingle | Ruirui Zhou Meiqi Chang Mengjun Shen Yang Cong Yu Chen Yin Wang Sonocatalytic Optimization of Titanium‐Based Therapeutic Nanomedicine Advanced Science sonocatalytic sonodynamic therapy sonosensitizers titanium‐based nanomedicine ultrasound therapy |
| title | Sonocatalytic Optimization of Titanium‐Based Therapeutic Nanomedicine |
| title_full | Sonocatalytic Optimization of Titanium‐Based Therapeutic Nanomedicine |
| title_fullStr | Sonocatalytic Optimization of Titanium‐Based Therapeutic Nanomedicine |
| title_full_unstemmed | Sonocatalytic Optimization of Titanium‐Based Therapeutic Nanomedicine |
| title_short | Sonocatalytic Optimization of Titanium‐Based Therapeutic Nanomedicine |
| title_sort | sonocatalytic optimization of titanium based therapeutic nanomedicine |
| topic | sonocatalytic sonodynamic therapy sonosensitizers titanium‐based nanomedicine ultrasound therapy |
| url | https://doi.org/10.1002/advs.202301764 |
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