High-viscosity bone cement for vertebral compression fractures: a prospective study on intravertebral diffusion and leakage of bone cement

Abstract Background Bone cement leakage causes severe complication following percutaneous vertebroplasty. This study probed the diffusion and leakage status of bone cement injected within diverged time duration, so as to find the optimal injection time for bone cement. Methods A total of 70 patients...

Full description

Bibliographic Details
Main Authors: Meiyong Wang, Qunhua Jin
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Musculoskeletal Disorders
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12891-020-03613-7
_version_ 1818160939947524096
author Meiyong Wang
Qunhua Jin
author_facet Meiyong Wang
Qunhua Jin
author_sort Meiyong Wang
collection DOAJ
description Abstract Background Bone cement leakage causes severe complication following percutaneous vertebroplasty. This study probed the diffusion and leakage status of bone cement injected within diverged time duration, so as to find the optimal injection time for bone cement. Methods A total of 70 patients with osteoporotic vertebral compression fractures with a symptom of low back pain, who underwent treatment at hospital were enrolled in this study. Patients were randomized into three groups: < 180 s, 180–300, and > 300 s of injection time duration from the beginning to the completion of the injection. The scenarios of vertebral bone cement leakage and diffusion were inspected using postoperative CT. Results The diffusion coefficient was higher in group A than in group B whereas it was higher in group B than in group C, but without statistical significance among the three groups. The leakage rate was without statistical significance among the three groups. The injection time of bone cement was negatively correlated with the diffusion coefficient, at the correlation coefficient of − 0.253. Conclusions The diffusion coefficient of high-viscosity bone cement is negatively correlated with the injection time, and the leakage rate of high-viscosity bone cement does not reduce with the prolongation of injection time.
first_indexed 2024-12-11T16:09:51Z
format Article
id doaj.art-336b988f9d5b42a8aea7d9766b05d863
institution Directory Open Access Journal
issn 1471-2474
language English
last_indexed 2024-12-11T16:09:51Z
publishDate 2020-09-01
publisher BMC
record_format Article
series BMC Musculoskeletal Disorders
spelling doaj.art-336b988f9d5b42a8aea7d9766b05d8632022-12-22T00:59:05ZengBMCBMC Musculoskeletal Disorders1471-24742020-09-012111510.1186/s12891-020-03613-7High-viscosity bone cement for vertebral compression fractures: a prospective study on intravertebral diffusion and leakage of bone cementMeiyong Wang0Qunhua Jin1Qilu Hospital, Cheeloo College of Medicine, Shandong UniversityGeneral hospital of Ningxia Medical UniversityAbstract Background Bone cement leakage causes severe complication following percutaneous vertebroplasty. This study probed the diffusion and leakage status of bone cement injected within diverged time duration, so as to find the optimal injection time for bone cement. Methods A total of 70 patients with osteoporotic vertebral compression fractures with a symptom of low back pain, who underwent treatment at hospital were enrolled in this study. Patients were randomized into three groups: < 180 s, 180–300, and > 300 s of injection time duration from the beginning to the completion of the injection. The scenarios of vertebral bone cement leakage and diffusion were inspected using postoperative CT. Results The diffusion coefficient was higher in group A than in group B whereas it was higher in group B than in group C, but without statistical significance among the three groups. The leakage rate was without statistical significance among the three groups. The injection time of bone cement was negatively correlated with the diffusion coefficient, at the correlation coefficient of − 0.253. Conclusions The diffusion coefficient of high-viscosity bone cement is negatively correlated with the injection time, and the leakage rate of high-viscosity bone cement does not reduce with the prolongation of injection time.http://link.springer.com/article/10.1186/s12891-020-03613-7Percutaneous vertebroplastyBone cement, leakage, osteoporosis, elderly, pain, diffusion
spellingShingle Meiyong Wang
Qunhua Jin
High-viscosity bone cement for vertebral compression fractures: a prospective study on intravertebral diffusion and leakage of bone cement
BMC Musculoskeletal Disorders
Percutaneous vertebroplasty
Bone cement, leakage, osteoporosis, elderly, pain, diffusion
title High-viscosity bone cement for vertebral compression fractures: a prospective study on intravertebral diffusion and leakage of bone cement
title_full High-viscosity bone cement for vertebral compression fractures: a prospective study on intravertebral diffusion and leakage of bone cement
title_fullStr High-viscosity bone cement for vertebral compression fractures: a prospective study on intravertebral diffusion and leakage of bone cement
title_full_unstemmed High-viscosity bone cement for vertebral compression fractures: a prospective study on intravertebral diffusion and leakage of bone cement
title_short High-viscosity bone cement for vertebral compression fractures: a prospective study on intravertebral diffusion and leakage of bone cement
title_sort high viscosity bone cement for vertebral compression fractures a prospective study on intravertebral diffusion and leakage of bone cement
topic Percutaneous vertebroplasty
Bone cement, leakage, osteoporosis, elderly, pain, diffusion
url http://link.springer.com/article/10.1186/s12891-020-03613-7
work_keys_str_mv AT meiyongwang highviscositybonecementforvertebralcompressionfracturesaprospectivestudyonintravertebraldiffusionandleakageofbonecement
AT qunhuajin highviscositybonecementforvertebralcompressionfracturesaprospectivestudyonintravertebraldiffusionandleakageofbonecement