Complement Inhibition Therapy and Dialytic Strategies in Paroxysmal Nocturnal Hemoglobinuria: The Nephrologist’s Opinion

Complement Inhibition Therapy and Dialytic Strategies in Paroxysmal Nocturnal Hemoglobinuria: The Nephrologist’s Opinion

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare clonal disease that presents an estimated incidence of 1.3 cases per million per year, with a prevalence of 15.9 cases per million. It is characterized by hemolysis, bone marrow dysfunction with peripheral blood cytopenia, hypercoagulability, throm...

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Bibliographic Details
Main Authors: Guido Gembillo, Rossella Siligato, Valeria Cernaro, Domenico Santoro
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Journal of Clinical Medicine
Subjects:
paroxysmal nocturnal hemoglobinuria
complement inhibition
eculizumab
ravulizumab
hemodialysis
Online Access:https://www.mdpi.com/2077-0383/9/5/1261

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