Effects of hysteroscopic septum incision versus expectant management on IVF outcomes in women with complete septate uterus: a retrospective study
Abstract Objective This retrospective study aimed to assess the impact of hysteroscopic septum incision on in vitro fertilization (IVF) outcomes among infertile women diagnosed with a complete septate uterus and no history of recurrent pregnancy loss. Methods The study was conducted at a tertiary re...
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| Format: | Article |
| Language: | English |
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BMC
2024-03-01
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| Series: | BMC Women's Health |
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| Online Access: | https://doi.org/10.1186/s12905-024-03022-1 |
| _version_ | 1797233240014061568 |
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| author | Jiajia Zhang Jia Kang Xueling Song Shuo Yang Yan Yang Jie Qiao Caihong Ma |
| author_facet | Jiajia Zhang Jia Kang Xueling Song Shuo Yang Yan Yang Jie Qiao Caihong Ma |
| author_sort | Jiajia Zhang |
| collection | DOAJ |
| description | Abstract Objective This retrospective study aimed to assess the impact of hysteroscopic septum incision on in vitro fertilization (IVF) outcomes among infertile women diagnosed with a complete septate uterus and no history of recurrent pregnancy loss. Methods The study was conducted at a tertiary reproductive center affiliated with a university hospital and involved 78 women with a complete septate uterus. Among them, 34 women underwent hysteroscopic septum incision, while 44 women opted for expectant management. The primary outcome measure was the live birth rate, while secondary outcomes included clinical pregnancy rate, preterm birth rate, miscarriage rate, and ongoing pregnancy rate. Results Women who underwent hysteroscopic septum incision demonstrated a comparable likelihood of achieving a live birth compared to those managed expectantly (25% vs. 25%, Relative Risk (RR): 1.000, 95% Confidence Interval (CI): 0.822 to 1.216). No preterm births occurred in either group. The clinical pregnancy rate, ongoing pregnancy rate, and miscarriage rate showed no significant differences between the surgical group and the expectant management group. Subgroup analyses based on the type of embryo transferred also revealed no significant differences in outcomes. Conclusions Hysteroscopic septum incision does not appear to yield improved IVF outcomes compared to expectant management in infertile women with a complete septate uterus and no history of recurrent pregnancy loss. |
| first_indexed | 2024-04-24T16:13:01Z |
| format | Article |
| id | doaj.art-336febec904d47788c6ec7c72f248221 |
| institution | Directory Open Access Journal |
| issn | 1472-6874 |
| language | English |
| last_indexed | 2024-04-24T16:13:01Z |
| publishDate | 2024-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Women's Health |
| spelling | doaj.art-336febec904d47788c6ec7c72f2482212024-03-31T11:34:01ZengBMCBMC Women's Health1472-68742024-03-012411710.1186/s12905-024-03022-1Effects of hysteroscopic septum incision versus expectant management on IVF outcomes in women with complete septate uterus: a retrospective studyJiajia Zhang0Jia Kang1Xueling Song2Shuo Yang3Yan Yang4Jie Qiao5Caihong Ma6Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third HospitalCenter for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third HospitalCenter for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third HospitalCenter for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third HospitalCenter for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third HospitalCenter for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third HospitalCenter for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third HospitalAbstract Objective This retrospective study aimed to assess the impact of hysteroscopic septum incision on in vitro fertilization (IVF) outcomes among infertile women diagnosed with a complete septate uterus and no history of recurrent pregnancy loss. Methods The study was conducted at a tertiary reproductive center affiliated with a university hospital and involved 78 women with a complete septate uterus. Among them, 34 women underwent hysteroscopic septum incision, while 44 women opted for expectant management. The primary outcome measure was the live birth rate, while secondary outcomes included clinical pregnancy rate, preterm birth rate, miscarriage rate, and ongoing pregnancy rate. Results Women who underwent hysteroscopic septum incision demonstrated a comparable likelihood of achieving a live birth compared to those managed expectantly (25% vs. 25%, Relative Risk (RR): 1.000, 95% Confidence Interval (CI): 0.822 to 1.216). No preterm births occurred in either group. The clinical pregnancy rate, ongoing pregnancy rate, and miscarriage rate showed no significant differences between the surgical group and the expectant management group. Subgroup analyses based on the type of embryo transferred also revealed no significant differences in outcomes. Conclusions Hysteroscopic septum incision does not appear to yield improved IVF outcomes compared to expectant management in infertile women with a complete septate uterus and no history of recurrent pregnancy loss.https://doi.org/10.1186/s12905-024-03022-1Septate uterusSeptum incisionIn vitro Fertilization |
| spellingShingle | Jiajia Zhang Jia Kang Xueling Song Shuo Yang Yan Yang Jie Qiao Caihong Ma Effects of hysteroscopic septum incision versus expectant management on IVF outcomes in women with complete septate uterus: a retrospective study BMC Women's Health Septate uterus Septum incision In vitro Fertilization |
| title | Effects of hysteroscopic septum incision versus expectant management on IVF outcomes in women with complete septate uterus: a retrospective study |
| title_full | Effects of hysteroscopic septum incision versus expectant management on IVF outcomes in women with complete septate uterus: a retrospective study |
| title_fullStr | Effects of hysteroscopic septum incision versus expectant management on IVF outcomes in women with complete septate uterus: a retrospective study |
| title_full_unstemmed | Effects of hysteroscopic septum incision versus expectant management on IVF outcomes in women with complete septate uterus: a retrospective study |
| title_short | Effects of hysteroscopic septum incision versus expectant management on IVF outcomes in women with complete septate uterus: a retrospective study |
| title_sort | effects of hysteroscopic septum incision versus expectant management on ivf outcomes in women with complete septate uterus a retrospective study |
| topic | Septate uterus Septum incision In vitro Fertilization |
| url | https://doi.org/10.1186/s12905-024-03022-1 |
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