Prevalence and antimicrobial susceptibility pattern of methicillin-resistant Staphylococcus aureus (MRSA) in AL-Yarmook teaching hospital-Baghdad
Nosocomial infection is a major problem in the world today. Methicillin- resistant Staphylococcus aureus (MRSA) strains, usually resistant to several antibiotics and also intrinsic resistance to ß- lactam antibiotics, shows a particular ability to spread in hospitals and now present in most of the...
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| Format: | Article |
| Language: | English |
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College of Pharmacy / Mustansiriyah University
2013-06-01
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| Series: | Al-Mustansiriyah Journal of Pharmaceutical Sciences |
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| Online Access: | https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/191 |
| _version_ | 1797223911486652416 |
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| author | Baydaa Hameed Abdullah |
| author_facet | Baydaa Hameed Abdullah |
| author_sort | Baydaa Hameed Abdullah |
| collection | DOAJ |
| description |
Nosocomial infection is a major problem in the world today. Methicillin- resistant Staphylococcus aureus (MRSA) strains, usually resistant to several antibiotics and also intrinsic resistance to ß- lactam antibiotics, shows a particular ability to spread in hospitals and now present in most of the countries. The present study was carried out to investigate the prevalence of MRSA and their rate of resistance to different antistaphylococcal antibiotics.
Between Decembers 2009and April 2011, the clinical specimens submitted at the microbiology laboratory were processed and all Staphylococcus aureus (S. aureus) isolates were included in this study.
All isolates were identified morphologically and biochemically by standard laboratory procedures and antibiotic susceptibility pattern including oxacillin was determined by modified Kirby Bauer disc diffusion method.
Out of a total of 337 Staphylococcus aureus strains isolated from various clinical samples, 140(41.54%) were found to be Methicillin- resistant. Among MRSA isolates, 86(46.99%) were from different inpatient departments, whereas, 54 (35.06%) of the isolates were from outpatients.
All MRSA were resistant to penicillin. About 70% of the MRSA strains were resistant to cephalexin, ciprofloxacin and cloxacillin ,while less than 10% of them were resistant to amikacin and tetracycline. Many MRSA strains were multidrug resistant. However, no strains were resistant to vancomycin.
This report showed a high prevalence of MRSA in Al-Yarmook hospital. To reduce the prevalence of MRSA, regular surveillance of hospital acquired infection and isolation is the need of the hour.
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| first_indexed | 2024-04-24T13:44:45Z |
| format | Article |
| id | doaj.art-33743d3185e54ce6bb1bfcf4abbce028 |
| institution | Directory Open Access Journal |
| issn | 1815-0993 2959-183X |
| language | English |
| last_indexed | 2024-04-24T13:44:45Z |
| publishDate | 2013-06-01 |
| publisher | College of Pharmacy / Mustansiriyah University |
| record_format | Article |
| series | Al-Mustansiriyah Journal of Pharmaceutical Sciences |
| spelling | doaj.art-33743d3185e54ce6bb1bfcf4abbce0282024-04-04T06:58:38ZengCollege of Pharmacy / Mustansiriyah UniversityAl-Mustansiriyah Journal of Pharmaceutical Sciences1815-09932959-183X2013-06-0113110.32947/ajps.v13i1.191Prevalence and antimicrobial susceptibility pattern of methicillin-resistant Staphylococcus aureus (MRSA) in AL-Yarmook teaching hospital-BaghdadBaydaa Hameed Abdullah0Department of clinical and laboratory sciences, Pharmacy college, Al Mustansiriyah University Nosocomial infection is a major problem in the world today. Methicillin- resistant Staphylococcus aureus (MRSA) strains, usually resistant to several antibiotics and also intrinsic resistance to ß- lactam antibiotics, shows a particular ability to spread in hospitals and now present in most of the countries. The present study was carried out to investigate the prevalence of MRSA and their rate of resistance to different antistaphylococcal antibiotics. Between Decembers 2009and April 2011, the clinical specimens submitted at the microbiology laboratory were processed and all Staphylococcus aureus (S. aureus) isolates were included in this study. All isolates were identified morphologically and biochemically by standard laboratory procedures and antibiotic susceptibility pattern including oxacillin was determined by modified Kirby Bauer disc diffusion method. Out of a total of 337 Staphylococcus aureus strains isolated from various clinical samples, 140(41.54%) were found to be Methicillin- resistant. Among MRSA isolates, 86(46.99%) were from different inpatient departments, whereas, 54 (35.06%) of the isolates were from outpatients. All MRSA were resistant to penicillin. About 70% of the MRSA strains were resistant to cephalexin, ciprofloxacin and cloxacillin ,while less than 10% of them were resistant to amikacin and tetracycline. Many MRSA strains were multidrug resistant. However, no strains were resistant to vancomycin. This report showed a high prevalence of MRSA in Al-Yarmook hospital. To reduce the prevalence of MRSA, regular surveillance of hospital acquired infection and isolation is the need of the hour. https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/191Nosocomial infection, methicillin-resistant Staphylococcus aureus (MRSA), multidrug resistant. |
| spellingShingle | Baydaa Hameed Abdullah Prevalence and antimicrobial susceptibility pattern of methicillin-resistant Staphylococcus aureus (MRSA) in AL-Yarmook teaching hospital-Baghdad Al-Mustansiriyah Journal of Pharmaceutical Sciences Nosocomial infection, methicillin-resistant Staphylococcus aureus (MRSA), multidrug resistant. |
| title | Prevalence and antimicrobial susceptibility pattern of methicillin-resistant Staphylococcus aureus (MRSA) in AL-Yarmook teaching hospital-Baghdad |
| title_full | Prevalence and antimicrobial susceptibility pattern of methicillin-resistant Staphylococcus aureus (MRSA) in AL-Yarmook teaching hospital-Baghdad |
| title_fullStr | Prevalence and antimicrobial susceptibility pattern of methicillin-resistant Staphylococcus aureus (MRSA) in AL-Yarmook teaching hospital-Baghdad |
| title_full_unstemmed | Prevalence and antimicrobial susceptibility pattern of methicillin-resistant Staphylococcus aureus (MRSA) in AL-Yarmook teaching hospital-Baghdad |
| title_short | Prevalence and antimicrobial susceptibility pattern of methicillin-resistant Staphylococcus aureus (MRSA) in AL-Yarmook teaching hospital-Baghdad |
| title_sort | prevalence and antimicrobial susceptibility pattern of methicillin resistant staphylococcus aureus mrsa in al yarmook teaching hospital baghdad |
| topic | Nosocomial infection, methicillin-resistant Staphylococcus aureus (MRSA), multidrug resistant. |
| url | https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/191 |
| work_keys_str_mv | AT baydaahameedabdullah prevalenceandantimicrobialsusceptibilitypatternofmethicillinresistantstaphylococcusaureusmrsainalyarmookteachinghospitalbaghdad |