Primary care providers’ preferences for the communication and management of actionable genomic findings from a research biobank
Purpose: Little is known about non-genetics health care specialists’ attitudes toward the return and utilization of actionable genomic results from a research biobank. We surveyed primary care providers (PCPs) to explore their perspectives on these results and their preferences for return. Methods:...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | Genetics in Medicine Open |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2949774423008397 |
| _version_ | 1797341886358224896 |
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| author | Elizabeth L. Kudron Sridharan Raghavan Yee Ming Lee Jan T. Lowery |
| author_facet | Elizabeth L. Kudron Sridharan Raghavan Yee Ming Lee Jan T. Lowery |
| author_sort | Elizabeth L. Kudron |
| collection | DOAJ |
| description | Purpose: Little is known about non-genetics health care specialists’ attitudes toward the return and utilization of actionable genomic results from a research biobank. We surveyed primary care providers (PCPs) to explore their perspectives on these results and their preferences for return. Methods: We administered a paper and web-based 27-question survey to PCPs residing locally and caring for adult patients. Recruitment was conducted in person and by email, focusing on PCPs likely to interact with results generated by our institution’s biobank. Results: Of the ∼482 PCPs contacted, 77 (16%) returned surveys. Although most respondents (90%) prefer that a genetics specialist be involved in communicating biobank-generated genomic results to patients, about 40% of respondents reported that a PCP shares the responsibility to discuss these results along with other specialists. A majority of respondents (74%) felt uncomfortable communicating these results to patients. However, respondents reported significantly greater comfort with this process when offered targeted educational resources (62% with vs 10% without resources; P < 10−5). Conclusion: PCPs recognize the need to engage with their patients’ biobank-generated genomic results but feel uncomfortable in doing so. Relevant resources are needed to improve PCPs’ confidence in the use of these types of results to affect patient care. |
| first_indexed | 2024-03-08T10:25:27Z |
| format | Article |
| id | doaj.art-3375453bf6864a02bd0be1f28a5d32cc |
| institution | Directory Open Access Journal |
| issn | 2949-7744 |
| language | English |
| last_indexed | 2024-03-08T10:25:27Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Genetics in Medicine Open |
| spelling | doaj.art-3375453bf6864a02bd0be1f28a5d32cc2024-01-27T07:13:45ZengElsevierGenetics in Medicine Open2949-77442023-01-0111100830Primary care providers’ preferences for the communication and management of actionable genomic findings from a research biobankElizabeth L. Kudron0Sridharan Raghavan1Yee Ming Lee2Jan T. Lowery3Department of Biomedical Informatics, University of Colorado School of Medicine, Aurora, CO; Colorado Center for Personalized Medicine, University of Colorado, Aurora, CO; Section of General Pediatrics, Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO; Correspondence and requests for materials should be addressed to Elizabeth L. Kudron, 1890 N Revere Court, Aurora, CO, 80045.Colorado Center for Personalized Medicine, University of Colorado, Aurora, CO; VA Eastern Colorado Health Care System, Aurora, CO; Division of General Internal Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, COColorado Center for Personalized Medicine, University of Colorado, Aurora, CO; Department of Clinical Pharmacy, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, COColorado Center for Personalized Medicine, University of Colorado, Aurora, CO; School of Public Health and Cancer Center, University of Colorado, Aurora, COPurpose: Little is known about non-genetics health care specialists’ attitudes toward the return and utilization of actionable genomic results from a research biobank. We surveyed primary care providers (PCPs) to explore their perspectives on these results and their preferences for return. Methods: We administered a paper and web-based 27-question survey to PCPs residing locally and caring for adult patients. Recruitment was conducted in person and by email, focusing on PCPs likely to interact with results generated by our institution’s biobank. Results: Of the ∼482 PCPs contacted, 77 (16%) returned surveys. Although most respondents (90%) prefer that a genetics specialist be involved in communicating biobank-generated genomic results to patients, about 40% of respondents reported that a PCP shares the responsibility to discuss these results along with other specialists. A majority of respondents (74%) felt uncomfortable communicating these results to patients. However, respondents reported significantly greater comfort with this process when offered targeted educational resources (62% with vs 10% without resources; P < 10−5). Conclusion: PCPs recognize the need to engage with their patients’ biobank-generated genomic results but feel uncomfortable in doing so. Relevant resources are needed to improve PCPs’ confidence in the use of these types of results to affect patient care.http://www.sciencedirect.com/science/article/pii/S2949774423008397BiobankGeneticsPharmacogeneticsPrimary care providerResearch |
| spellingShingle | Elizabeth L. Kudron Sridharan Raghavan Yee Ming Lee Jan T. Lowery Primary care providers’ preferences for the communication and management of actionable genomic findings from a research biobank Genetics in Medicine Open Biobank Genetics Pharmacogenetics Primary care provider Research |
| title | Primary care providers’ preferences for the communication and management of actionable genomic findings from a research biobank |
| title_full | Primary care providers’ preferences for the communication and management of actionable genomic findings from a research biobank |
| title_fullStr | Primary care providers’ preferences for the communication and management of actionable genomic findings from a research biobank |
| title_full_unstemmed | Primary care providers’ preferences for the communication and management of actionable genomic findings from a research biobank |
| title_short | Primary care providers’ preferences for the communication and management of actionable genomic findings from a research biobank |
| title_sort | primary care providers preferences for the communication and management of actionable genomic findings from a research biobank |
| topic | Biobank Genetics Pharmacogenetics Primary care provider Research |
| url | http://www.sciencedirect.com/science/article/pii/S2949774423008397 |
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