Early Changes in Transcriptomic Profiles in Synaptodendrosomes Reveal Aberrant Synaptic Functions in Alzheimer’s Disease

Early Changes in Transcriptomic Profiles in Synaptodendrosomes Reveal Aberrant Synaptic Functions in Alzheimer’s Disease

Alzheimer’s disease (AD) is one of the most prevalent neurodegenerative disorders characterized by the progressive decline of cognitive functions, and is closely associated with the dysfunction of synapses, which comprise the basic structure that mediates the communication between neurons. Although...

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Bibliographic Details
Main Authors: Xueqi Qu, Li Lin, Wanying Yi, Changyu Sun, Yuewen Chen, Yu Chen
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
neurodegenerative disease
local translation
synapse loss
synaptic transmission
Online Access:https://www.mdpi.com/1422-0067/23/16/8888

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