Enhanced upper genital tract pathologies by blocking Tim-3 and PD-L1 signaling pathways in mice intravaginally infected with <it>Chlamydia muridarum</it>

Enhanced upper genital tract pathologies by blocking Tim-3 and PD-L1 signaling pathways in mice intravaginally infected with <it>Chlamydia muridarum</it>

<p>Abstract</p> <p>Background</p> <p>Although Tim-3 & PD-L1 signaling pathways play important roles in negatively regulating immune responses, their roles in chlamydial infection have not been evaluated.</p> <p>Methods</p> <p>Neutralization a...

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Bibliographic Details
Main Authors: Peng Bo, Lu Chunxue, Tang Lingli, Yeh I-Tien, He Zhimin, Wu Yimou, Zhong Guangming
Format: Article
Language:English
Published: BMC 2011-12-01
Series:BMC Infectious Diseases
Subjects:
<it>Chlamydia muridarum</it>
Oviduct pathology
Tim-3 &
PD-L1 signaling pathways
Online Access:http://www.biomedcentral.com/1471-2334/11/347

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