Deciphering cell–cell interactions and communication in the tumor microenvironment and unraveling intratumoral genetic heterogeneity via single-cell genomic sequencing

Deciphering cell–cell interactions and communication in the tumor microenvironment and unraveling intratumoral genetic heterogeneity via single-cell genomic sequencing

ABSTRACTA tumor’s heterogeneity has important implications in terms of its clonal origin, progression, stemness, and drug resistance. Therefore, because of its significance in treatment, it is important to understand the gene expression pattern of a single cell, track gene expression or mutation in...

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Bibliographic Details
Main Authors: Ya-Hong Cao, Jie Ding, Qing-Hai Tang, Jie Zhang, Zhong-Yan Huang, Xiao-Mei Tang, Ji-Bin Liu, Yu-Shui Ma, Da Fu
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Bioengineered
Subjects:
ScRNA-seq
TME
heterogeneity
genome evolution
cell-cell interactions
Online Access:https://www.tandfonline.com/doi/10.1080/21655979.2023.2185434

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