From genes to ecosystems: Decoding plant tolerance mechanisms to arsenic stress
Arsenic (As), a metalloid of considerable toxicity, has become increasingly bioavailable through anthropogenic activities, raising As contamination levels in groundwater and agricultural soils worldwide. This bioavailability has profound implications for plant biology and farming systems. As can det...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-04-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024051715 |
| _version_ | 1827292705961541632 |
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| author | Celeste Gracia-Rodriguez Carlos Lopez-Ortiz Gerardo Flores-Iga Lizbeth Ibarra-Muñoz Padma Nimmakayala Umesh K. Reddy Nagamani Balagurusamy |
| author_facet | Celeste Gracia-Rodriguez Carlos Lopez-Ortiz Gerardo Flores-Iga Lizbeth Ibarra-Muñoz Padma Nimmakayala Umesh K. Reddy Nagamani Balagurusamy |
| author_sort | Celeste Gracia-Rodriguez |
| collection | DOAJ |
| description | Arsenic (As), a metalloid of considerable toxicity, has become increasingly bioavailable through anthropogenic activities, raising As contamination levels in groundwater and agricultural soils worldwide. This bioavailability has profound implications for plant biology and farming systems. As can detrimentally affect crop yield and pose risks of bioaccumulation and subsequent entry into the food chain. Upon exposure to As, plants initiate a multifaceted molecular response involving crucial signaling pathways, such as those mediated by calcium, mitogen-activated protein kinases, and various phytohormones (e.g., auxin, methyl jasmonate, cytokinin). These pathways, in turn, activate enzymes within the antioxidant system, which combat the reactive oxygen/nitrogen species (ROS and RNS) generated by As-induced stress. Plants exhibit a sophisticated genomic response to As, involving the upregulation of genes associated with uptake, chelation, and sequestration. Specific gene families, such as those coding for aquaglyceroporins and ABC transporters, are key in mediating As uptake and translocation within plant tissues. Moreover, we explore the gene regulatory networks that orchestrate the synthesis of phytochelatins and metallothioneins, which are crucial for As chelation and detoxification. Transcription factors, particularly those belonging to the MYB, NAC, and WRKY families, emerge as central regulators in activating As-responsive genes. On a post-translational level, we examine how ubiquitination pathways modulate the stability and function of proteins involved in As metabolism. By integrating omics findings, this review provides a comprehensive overview of the complex genomic landscape that defines plant responses to As. Knowledge gained from these genomic and epigenetic insights is pivotal for developing biotechnological strategies to enhance crop As tolerance. |
| first_indexed | 2024-04-24T13:10:24Z |
| format | Article |
| id | doaj.art-3382c635406b4d4e98f42fb3829a53f0 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-24T13:10:24Z |
| publishDate | 2024-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-3382c635406b4d4e98f42fb3829a53f02024-04-05T04:41:23ZengElsevierHeliyon2405-84402024-04-01107e29140From genes to ecosystems: Decoding plant tolerance mechanisms to arsenic stressCeleste Gracia-Rodriguez0Carlos Lopez-Ortiz1Gerardo Flores-Iga2Lizbeth Ibarra-Muñoz3Padma Nimmakayala4Umesh K. Reddy5Nagamani Balagurusamy6Laboratorio de Biorremediación, Facultad de Ciencias Biológicas, Universidad Autónoma de Coahuila, Torreón, Mexico; Gus R. Douglass Institute and Department of Biology, West Virginia State University, Institute, Dunbar, WV 25112-1000, USAGus R. Douglass Institute and Department of Biology, West Virginia State University, Institute, Dunbar, WV 25112-1000, USALaboratorio de Biorremediación, Facultad de Ciencias Biológicas, Universidad Autónoma de Coahuila, Torreón, Mexico; Gus R. Douglass Institute and Department of Biology, West Virginia State University, Institute, Dunbar, WV 25112-1000, USALaboratorio de Biorremediación, Facultad de Ciencias Biológicas, Universidad Autónoma de Coahuila, Torreón, MexicoGus R. Douglass Institute and Department of Biology, West Virginia State University, Institute, Dunbar, WV 25112-1000, USAGus R. Douglass Institute and Department of Biology, West Virginia State University, Institute, Dunbar, WV 25112-1000, USA; Corresponding author.Laboratorio de Biorremediación, Facultad de Ciencias Biológicas, Universidad Autónoma de Coahuila, Torreón, Mexico; Corresponding author.Arsenic (As), a metalloid of considerable toxicity, has become increasingly bioavailable through anthropogenic activities, raising As contamination levels in groundwater and agricultural soils worldwide. This bioavailability has profound implications for plant biology and farming systems. As can detrimentally affect crop yield and pose risks of bioaccumulation and subsequent entry into the food chain. Upon exposure to As, plants initiate a multifaceted molecular response involving crucial signaling pathways, such as those mediated by calcium, mitogen-activated protein kinases, and various phytohormones (e.g., auxin, methyl jasmonate, cytokinin). These pathways, in turn, activate enzymes within the antioxidant system, which combat the reactive oxygen/nitrogen species (ROS and RNS) generated by As-induced stress. Plants exhibit a sophisticated genomic response to As, involving the upregulation of genes associated with uptake, chelation, and sequestration. Specific gene families, such as those coding for aquaglyceroporins and ABC transporters, are key in mediating As uptake and translocation within plant tissues. Moreover, we explore the gene regulatory networks that orchestrate the synthesis of phytochelatins and metallothioneins, which are crucial for As chelation and detoxification. Transcription factors, particularly those belonging to the MYB, NAC, and WRKY families, emerge as central regulators in activating As-responsive genes. On a post-translational level, we examine how ubiquitination pathways modulate the stability and function of proteins involved in As metabolism. By integrating omics findings, this review provides a comprehensive overview of the complex genomic landscape that defines plant responses to As. Knowledge gained from these genomic and epigenetic insights is pivotal for developing biotechnological strategies to enhance crop As tolerance.http://www.sciencedirect.com/science/article/pii/S2405844024051715Arsenic stressAbiotic stressPlant stress responseGenomic and molecular mechanismsDefense mechanismsArsenic toxicity |
| spellingShingle | Celeste Gracia-Rodriguez Carlos Lopez-Ortiz Gerardo Flores-Iga Lizbeth Ibarra-Muñoz Padma Nimmakayala Umesh K. Reddy Nagamani Balagurusamy From genes to ecosystems: Decoding plant tolerance mechanisms to arsenic stress Heliyon Arsenic stress Abiotic stress Plant stress response Genomic and molecular mechanisms Defense mechanisms Arsenic toxicity |
| title | From genes to ecosystems: Decoding plant tolerance mechanisms to arsenic stress |
| title_full | From genes to ecosystems: Decoding plant tolerance mechanisms to arsenic stress |
| title_fullStr | From genes to ecosystems: Decoding plant tolerance mechanisms to arsenic stress |
| title_full_unstemmed | From genes to ecosystems: Decoding plant tolerance mechanisms to arsenic stress |
| title_short | From genes to ecosystems: Decoding plant tolerance mechanisms to arsenic stress |
| title_sort | from genes to ecosystems decoding plant tolerance mechanisms to arsenic stress |
| topic | Arsenic stress Abiotic stress Plant stress response Genomic and molecular mechanisms Defense mechanisms Arsenic toxicity |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024051715 |
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