MODERN APPROACHES TO THE TREATMENT OF HEPATIC METASTASES FROM NEUROENDOCRINE TUMORS (LITERATURE REVIEW)

Originating from cells of the diffuse neuroendocrine system, neuroendocrine tumors are able to produce biogenic amines and peptide hormones. Due to the significantly different list of biologically active compounds and level of activity of secretory cells in tumor tissues, their clinical manifestatio...

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Main Authors: O. V. Chistyakova, O. N. Solovyeva, D. Xiaodong, V. Yu. Kosyrev
Format: Article
Language:Russian
Published: Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University) 2018-03-01
Series:Сеченовский вестник
Subjects:
Online Access:https://www.sechenovmedj.com/jour/article/view/52
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author O. V. Chistyakova
O. N. Solovyeva
D. Xiaodong
V. Yu. Kosyrev
author_facet O. V. Chistyakova
O. N. Solovyeva
D. Xiaodong
V. Yu. Kosyrev
author_sort O. V. Chistyakova
collection DOAJ
description Originating from cells of the diffuse neuroendocrine system, neuroendocrine tumors are able to produce biogenic amines and peptide hormones. Due to the significantly different list of biologically active compounds and level of activity of secretory cells in tumor tissues, their clinical manifestations varies. Liver is one of the most frequent targeted organs for metastasizing this type of tumors, regardless of localization. After the patients being diagnosed, all the treatment measures are focused on two aspects. The first is to suppress the clinical symptoms and improve the living quality. The second one, an increase in life expectancy. Among all the potentially effectible treatments, surgical resection is the only one that may radically kill the disease. However, its application are limited in some cases. In this regard, in the strategy of therapeutic approaches of neuroendocrine tumors with metastases in the liver, a combination of medical, surgical and renal surgical methods comes to the fore.
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spelling doaj.art-3388fbe1808c4493bb502e2e43ca23172023-03-13T09:51:33ZrusFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)Сеченовский вестник2218-73322658-33482018-03-0101545951MODERN APPROACHES TO THE TREATMENT OF HEPATIC METASTASES FROM NEUROENDOCRINE TUMORS (LITERATURE REVIEW)O. V. Chistyakova0O. N. Solovyeva1D. Xiaodong2V. Yu. Kosyrev3N.N. Blokhin Russian Cancer Reseach CenterN.N. Blokhin Russian Cancer Reseach CenterI.M. Sechenov First Moscow State Medical UniversityI.M. Sechenov First Moscow State Medical UniversityOriginating from cells of the diffuse neuroendocrine system, neuroendocrine tumors are able to produce biogenic amines and peptide hormones. Due to the significantly different list of biologically active compounds and level of activity of secretory cells in tumor tissues, their clinical manifestations varies. Liver is one of the most frequent targeted organs for metastasizing this type of tumors, regardless of localization. After the patients being diagnosed, all the treatment measures are focused on two aspects. The first is to suppress the clinical symptoms and improve the living quality. The second one, an increase in life expectancy. Among all the potentially effectible treatments, surgical resection is the only one that may radically kill the disease. However, its application are limited in some cases. In this regard, in the strategy of therapeutic approaches of neuroendocrine tumors with metastases in the liver, a combination of medical, surgical and renal surgical methods comes to the fore.https://www.sechenovmedj.com/jour/article/view/52neuroendocrine tumorshepatic metastasescombination treatment
spellingShingle O. V. Chistyakova
O. N. Solovyeva
D. Xiaodong
V. Yu. Kosyrev
MODERN APPROACHES TO THE TREATMENT OF HEPATIC METASTASES FROM NEUROENDOCRINE TUMORS (LITERATURE REVIEW)
Сеченовский вестник
neuroendocrine tumors
hepatic metastases
combination treatment
title MODERN APPROACHES TO THE TREATMENT OF HEPATIC METASTASES FROM NEUROENDOCRINE TUMORS (LITERATURE REVIEW)
title_full MODERN APPROACHES TO THE TREATMENT OF HEPATIC METASTASES FROM NEUROENDOCRINE TUMORS (LITERATURE REVIEW)
title_fullStr MODERN APPROACHES TO THE TREATMENT OF HEPATIC METASTASES FROM NEUROENDOCRINE TUMORS (LITERATURE REVIEW)
title_full_unstemmed MODERN APPROACHES TO THE TREATMENT OF HEPATIC METASTASES FROM NEUROENDOCRINE TUMORS (LITERATURE REVIEW)
title_short MODERN APPROACHES TO THE TREATMENT OF HEPATIC METASTASES FROM NEUROENDOCRINE TUMORS (LITERATURE REVIEW)
title_sort modern approaches to the treatment of hepatic metastases from neuroendocrine tumors literature review
topic neuroendocrine tumors
hepatic metastases
combination treatment
url https://www.sechenovmedj.com/jour/article/view/52
work_keys_str_mv AT ovchistyakova modernapproachestothetreatmentofhepaticmetastasesfromneuroendocrinetumorsliteraturereview
AT onsolovyeva modernapproachestothetreatmentofhepaticmetastasesfromneuroendocrinetumorsliteraturereview
AT dxiaodong modernapproachestothetreatmentofhepaticmetastasesfromneuroendocrinetumorsliteraturereview
AT vyukosyrev modernapproachestothetreatmentofhepaticmetastasesfromneuroendocrinetumorsliteraturereview