Teodorico Borgognoni’s Formulary for Thirteenth Century Anesthetic Preparations

Teodorico Borgognoni was born in Lucca in 1205 and was appointed bishop of Bitonto and Cervia in 1262 and 1270. Following his father, he learned the art of surgery and collected relevant recipes in his most important work, entitled <i>Cyrurgia seu filia principis</i>. Among the disciplin...

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Main Authors: Valeria Cavalloro, Francesca Soddu, Sandro Baroni, Francesco Saverio Robustelli della Cuna, Eleonora Tavazzi, Emanuela Martino, Simona Collina
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/13/9/1913
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author Valeria Cavalloro
Francesca Soddu
Sandro Baroni
Francesco Saverio Robustelli della Cuna
Eleonora Tavazzi
Emanuela Martino
Simona Collina
author_facet Valeria Cavalloro
Francesca Soddu
Sandro Baroni
Francesco Saverio Robustelli della Cuna
Eleonora Tavazzi
Emanuela Martino
Simona Collina
author_sort Valeria Cavalloro
collection DOAJ
description Teodorico Borgognoni was born in Lucca in 1205 and was appointed bishop of Bitonto and Cervia in 1262 and 1270. Following his father, he learned the art of surgery and collected relevant recipes in his most important work, entitled <i>Cyrurgia seu filia principis</i>. Among the disciplines reported in this work, the most interesting and innovative is anesthesia. The recipes in this field contribute to Borbognoni’s consideration as the forerunner of modern anesthesia. Such recipes have been reported in other manuscripts from the Middle Ages, like Manuscript No. 1939. In the present work, we investigate the traditional preparations handed down in this manuscript, focusing on type of preparation and botanical ingredients. The results highlight that exploited ingredients can be divided into three groups: the first comprises plants already known for their narcotic effects, the second includes ingredients acting as an adjuvant for absorption or reducing the metabolism, and the last group includes ingredients not associated with biological activity to explain their presence in anesthetic recipes. This third group is of particular interest for future biological investigations. Our goal is to rekindle attention to the work of Teodorico Borgognoni on traditional preparation for anesthetic purposes: a topic often underestimated by ethnobotanical surveys.
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spelling doaj.art-338c8593aa5b4decb68425675b2c1e532023-11-19T11:38:02ZengMDPI AGLife2075-17292023-09-01139191310.3390/life13091913Teodorico Borgognoni’s Formulary for Thirteenth Century Anesthetic PreparationsValeria Cavalloro0Francesca Soddu1Sandro Baroni2Francesco Saverio Robustelli della Cuna3Eleonora Tavazzi4Emanuela Martino5Simona Collina6Department of Earth and Environmental Sciences, University of Pavia, Via S. Epifanio 14, 27100 Pavia, ItalyNeuroimmunology Laboratory, IRCCS Mondino Foundation, Via Mondino 2, 27100 Pavia, ItalyMaimeri Foundation, Corso Cristoforo Colombo 15, 20144 Milano, ItalyDepartment of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, ItalyMultiple Sclerosis Centre, IRCCS Mondino Foundation, Via Mondino 2, 27100 Pavia, ItalyDepartment of Earth and Environmental Sciences, University of Pavia, Via S. Epifanio 14, 27100 Pavia, ItalyDepartment of Drug Sciences, University of Pavia, Viale Taramelli 12, 27100 Pavia, ItalyTeodorico Borgognoni was born in Lucca in 1205 and was appointed bishop of Bitonto and Cervia in 1262 and 1270. Following his father, he learned the art of surgery and collected relevant recipes in his most important work, entitled <i>Cyrurgia seu filia principis</i>. Among the disciplines reported in this work, the most interesting and innovative is anesthesia. The recipes in this field contribute to Borbognoni’s consideration as the forerunner of modern anesthesia. Such recipes have been reported in other manuscripts from the Middle Ages, like Manuscript No. 1939. In the present work, we investigate the traditional preparations handed down in this manuscript, focusing on type of preparation and botanical ingredients. The results highlight that exploited ingredients can be divided into three groups: the first comprises plants already known for their narcotic effects, the second includes ingredients acting as an adjuvant for absorption or reducing the metabolism, and the last group includes ingredients not associated with biological activity to explain their presence in anesthetic recipes. This third group is of particular interest for future biological investigations. Our goal is to rekindle attention to the work of Teodorico Borgognoni on traditional preparation for anesthetic purposes: a topic often underestimated by ethnobotanical surveys.https://www.mdpi.com/2075-1729/13/9/1913Teodorico Borgognoniethnobotanyanesthesia
spellingShingle Valeria Cavalloro
Francesca Soddu
Sandro Baroni
Francesco Saverio Robustelli della Cuna
Eleonora Tavazzi
Emanuela Martino
Simona Collina
Teodorico Borgognoni’s Formulary for Thirteenth Century Anesthetic Preparations
Life
Teodorico Borgognoni
ethnobotany
anesthesia
title Teodorico Borgognoni’s Formulary for Thirteenth Century Anesthetic Preparations
title_full Teodorico Borgognoni’s Formulary for Thirteenth Century Anesthetic Preparations
title_fullStr Teodorico Borgognoni’s Formulary for Thirteenth Century Anesthetic Preparations
title_full_unstemmed Teodorico Borgognoni’s Formulary for Thirteenth Century Anesthetic Preparations
title_short Teodorico Borgognoni’s Formulary for Thirteenth Century Anesthetic Preparations
title_sort teodorico borgognoni s formulary for thirteenth century anesthetic preparations
topic Teodorico Borgognoni
ethnobotany
anesthesia
url https://www.mdpi.com/2075-1729/13/9/1913
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