Regulation of TAZ in cancer
ABSTRACT TAZ, a transcriptional coactivator with PDZ-binding motif, is encoded by WWTR1 gene (WW domain containing transcription regulator 1). TAZ is tightly regulated in the hippo pathway-dependent and -independent manner in response to a wide range of extracellular and intrinsic signals, including...
Main Authors: | Xin Zhou, Qun-Ying Lei |
---|---|
Format: | Article |
Language: | English |
Published: |
Oxford University Press
2016-07-01
|
Series: | Protein & Cell |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1007/s13238-016-0288-z |
Similar Items
-
YAP/TAZ Activation as a Target for Treating Metastatic Cancer
by: Janine S. A. Warren, et al.
Published: (2018-04-01) -
TAZ facilitates breast tumor growth by promoting an immune‐suppressive tumor microenvironment
by: Anat Gershoni, et al.
Published: (2023-12-01) -
Natural compounds targeting YAP/TAZ axis in cancer: Current state of art and challenges
by: Aviral Kumar, et al.
Published: (2024-05-01) -
Inhibition of TAZ impairs the migration ability of melanoma cells
by: Zhang Hao, et al.
Published: (2023-06-01) -
YAP/TAZ: a promising target for squamous cell carcinoma treatment
by: Dong X, et al.
Published: (2019-07-01)