Nevus Lipomatosis Cutaneous Superficialis: A Single-Center Case Series of 5 Patients
Background: Nevus lipomatosis cutaneous superficialis (NLCS) is a rare hamartoma of mature adipose tissue characterized by solitary or multiple, soft, skin-colored or yellowish lobules that may coalesce to give rise to plaques with a cerebriform surface. There are two clinical types: (1) multiple le...
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| Format: | Article |
| Language: | English |
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Karger Publishers
2018-05-01
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| Series: | Case Reports in Dermatology |
| Subjects: | |
| Online Access: | https://www.karger.com/Article/FullText/488900 |
| _version_ | 1818361274205995008 |
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| author | Homaid Alotaibi Fahad Alsaif Azhar Alali Mohammed Almashali Dana Al-Dabeeb Abdul-Aziz Altaweel |
| author_facet | Homaid Alotaibi Fahad Alsaif Azhar Alali Mohammed Almashali Dana Al-Dabeeb Abdul-Aziz Altaweel |
| author_sort | Homaid Alotaibi |
| collection | DOAJ |
| description | Background: Nevus lipomatosis cutaneous superficialis (NLCS) is a rare hamartoma of mature adipose tissue characterized by solitary or multiple, soft, skin-colored or yellowish lobules that may coalesce to give rise to plaques with a cerebriform surface. There are two clinical types: (1) multiple lesions that are usually presented in a segmental distribution and (2) a solitary papule or nodule. Aim and Objective: To study the clinical and histopathological features of 5 Saudi patients with NLCS. Method: A retrospective analysis of clinical data and histopathological findings of 5 cases of NLCS in King Khalid University Hospital between January 2011 and November 2016. Demographic and clinical data were obtained from the clinical case files. Slides and tissue blocks were retrieved. H&E- and EVG-stained slides were studied in all cases. Results: We identified 5 patients with NLCS, of whom 4 were female. The average age at diagnosis was 36 years. The mean duration of the lesion was 4.4 years. The most common location was the lower part of the body. Most of the cases were diagnosed as skin papilloma before skin biopsy. Surgical excision was effective and no recurrence was observed. Conclusion: This is the first study about this rare type of skin tumor in Saudi Arabia and highlights the need for awareness of this clinical condition among dermatologists. |
| first_indexed | 2024-12-13T21:14:05Z |
| format | Article |
| id | doaj.art-339937c9ee5a407bb55f57a032988791 |
| institution | Directory Open Access Journal |
| issn | 1662-6567 |
| language | English |
| last_indexed | 2024-12-13T21:14:05Z |
| publishDate | 2018-05-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Dermatology |
| spelling | doaj.art-339937c9ee5a407bb55f57a0329887912022-12-21T23:31:16ZengKarger PublishersCase Reports in Dermatology1662-65672018-05-0110213814410.1159/000488900488900Nevus Lipomatosis Cutaneous Superficialis: A Single-Center Case Series of 5 PatientsHomaid AlotaibiFahad AlsaifAzhar AlaliMohammed AlmashaliDana Al-DabeebAbdul-Aziz AltaweelBackground: Nevus lipomatosis cutaneous superficialis (NLCS) is a rare hamartoma of mature adipose tissue characterized by solitary or multiple, soft, skin-colored or yellowish lobules that may coalesce to give rise to plaques with a cerebriform surface. There are two clinical types: (1) multiple lesions that are usually presented in a segmental distribution and (2) a solitary papule or nodule. Aim and Objective: To study the clinical and histopathological features of 5 Saudi patients with NLCS. Method: A retrospective analysis of clinical data and histopathological findings of 5 cases of NLCS in King Khalid University Hospital between January 2011 and November 2016. Demographic and clinical data were obtained from the clinical case files. Slides and tissue blocks were retrieved. H&E- and EVG-stained slides were studied in all cases. Results: We identified 5 patients with NLCS, of whom 4 were female. The average age at diagnosis was 36 years. The mean duration of the lesion was 4.4 years. The most common location was the lower part of the body. Most of the cases were diagnosed as skin papilloma before skin biopsy. Surgical excision was effective and no recurrence was observed. Conclusion: This is the first study about this rare type of skin tumor in Saudi Arabia and highlights the need for awareness of this clinical condition among dermatologists.https://www.karger.com/Article/FullText/488900Nevus lipomatosis cutaneous superficialisSkin tumorHistopathology |
| spellingShingle | Homaid Alotaibi Fahad Alsaif Azhar Alali Mohammed Almashali Dana Al-Dabeeb Abdul-Aziz Altaweel Nevus Lipomatosis Cutaneous Superficialis: A Single-Center Case Series of 5 Patients Case Reports in Dermatology Nevus lipomatosis cutaneous superficialis Skin tumor Histopathology |
| title | Nevus Lipomatosis Cutaneous Superficialis: A Single-Center Case Series of 5 Patients |
| title_full | Nevus Lipomatosis Cutaneous Superficialis: A Single-Center Case Series of 5 Patients |
| title_fullStr | Nevus Lipomatosis Cutaneous Superficialis: A Single-Center Case Series of 5 Patients |
| title_full_unstemmed | Nevus Lipomatosis Cutaneous Superficialis: A Single-Center Case Series of 5 Patients |
| title_short | Nevus Lipomatosis Cutaneous Superficialis: A Single-Center Case Series of 5 Patients |
| title_sort | nevus lipomatosis cutaneous superficialis a single center case series of 5 patients |
| topic | Nevus lipomatosis cutaneous superficialis Skin tumor Histopathology |
| url | https://www.karger.com/Article/FullText/488900 |
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