Descriptive characteristics of gynecological malignant neoplasms
Background. Gynecological malignant neoplasms (GMN) are the leading disease group among female cancers.Objective: to characterize GMN in females occupationally exposed to ionizing radiation over prolonged periods.Materials and methods. The cohort considered in the study included females (n = 5689) w...
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| Format: | Article |
| Language: | Russian |
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ABV-press
2021-10-01
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| Series: | Опухоли женской репродуктивной системы |
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| Online Access: | https://ojrs.abvpress.ru/ojrs/article/view/866 |
| _version_ | 1797875990868787200 |
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| author | A. V. Rumyantseva M. V. Bannikova T. V. Azizova |
| author_facet | A. V. Rumyantseva M. V. Bannikova T. V. Azizova |
| author_sort | A. V. Rumyantseva |
| collection | DOAJ |
| description | Background. Gynecological malignant neoplasms (GMN) are the leading disease group among female cancers.Objective: to characterize GMN in females occupationally exposed to ionizing radiation over prolonged periods.Materials and methods. The cohort considered in the study included females (n = 5689) who had been hired at the Mayak Production Association in the period between 1948 and 1982. All these females were exposed to ionizing radiation over prolonged periods during their employment. They were followed up until 31.12.2018. Two groups of females were identified in the study cohort: the one with a verified GMN (the main group) and another one free of GMN (the control group). The occupational and reproductive characteristics were analyzed for the identified groups of females, and associations of GMN with various risk factors were assessed.Results. Among GMN the uterine corpus cancer had the top position. In 70 % of the females GMN were diagnosed during a menopausal period. The females of the main group demonstrated significantly higher frequency of underlying pre-malignant conditions (endometriosis, uterine myoma, endometrial hyperplastic processes, ovarian epidermoids, menopausal bleedings) compared to the control group.Conclusion. Studies of GMN in females occupationally exposed to ionizing radiation over prolonged periods for sure are of a certain scientific and practical interest. The findings can provide the basis for specialized cancer care for employees of the nuclear industry. |
| first_indexed | 2024-04-10T01:55:06Z |
| format | Article |
| id | doaj.art-3399c38db21649199676f6409b6b1494 |
| institution | Directory Open Access Journal |
| issn | 1994-4098 1999-8627 |
| language | Russian |
| last_indexed | 2024-04-10T01:55:06Z |
| publishDate | 2021-10-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Опухоли женской репродуктивной системы |
| spelling | doaj.art-3399c38db21649199676f6409b6b14942023-03-13T08:44:38ZrusABV-pressОпухоли женской репродуктивной системы1994-40981999-86272021-10-01173798810.17650/1994-4098-2021-17-3-79-88701Descriptive characteristics of gynecological malignant neoplasmsA. V. Rumyantseva0M. V. Bannikova1T. V. Azizova2ФГУП «Южно-Уральский институт биофизики Федерального медико-биологического агентства»ФГУП «Южно-Уральский институт биофизики Федерального медико-биологического агентства»ФГУП «Южно-Уральский институт биофизики Федерального медико-биологического агентства»Background. Gynecological malignant neoplasms (GMN) are the leading disease group among female cancers.Objective: to characterize GMN in females occupationally exposed to ionizing radiation over prolonged periods.Materials and methods. The cohort considered in the study included females (n = 5689) who had been hired at the Mayak Production Association in the period between 1948 and 1982. All these females were exposed to ionizing radiation over prolonged periods during their employment. They were followed up until 31.12.2018. Two groups of females were identified in the study cohort: the one with a verified GMN (the main group) and another one free of GMN (the control group). The occupational and reproductive characteristics were analyzed for the identified groups of females, and associations of GMN with various risk factors were assessed.Results. Among GMN the uterine corpus cancer had the top position. In 70 % of the females GMN were diagnosed during a menopausal period. The females of the main group demonstrated significantly higher frequency of underlying pre-malignant conditions (endometriosis, uterine myoma, endometrial hyperplastic processes, ovarian epidermoids, menopausal bleedings) compared to the control group.Conclusion. Studies of GMN in females occupationally exposed to ionizing radiation over prolonged periods for sure are of a certain scientific and practical interest. The findings can provide the basis for specialized cancer care for employees of the nuclear industry.https://ojrs.abvpress.ru/ojrs/article/view/866злокачественные новообразования женских половых органоврепродуктивное здоровье женщинзаболеваемостьпрофессиональное пролонгированное облучениепо «маяк» |
| spellingShingle | A. V. Rumyantseva M. V. Bannikova T. V. Azizova Descriptive characteristics of gynecological malignant neoplasms Опухоли женской репродуктивной системы злокачественные новообразования женских половых органов репродуктивное здоровье женщин заболеваемость профессиональное пролонгированное облучение по «маяк» |
| title | Descriptive characteristics of gynecological malignant neoplasms |
| title_full | Descriptive characteristics of gynecological malignant neoplasms |
| title_fullStr | Descriptive characteristics of gynecological malignant neoplasms |
| title_full_unstemmed | Descriptive characteristics of gynecological malignant neoplasms |
| title_short | Descriptive characteristics of gynecological malignant neoplasms |
| title_sort | descriptive characteristics of gynecological malignant neoplasms |
| topic | злокачественные новообразования женских половых органов репродуктивное здоровье женщин заболеваемость профессиональное пролонгированное облучение по «маяк» |
| url | https://ojrs.abvpress.ru/ojrs/article/view/866 |
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