Structures of mouse and human GITR–GITRL complexes reveal unique TNF superfamily interactions
Glucocorticoid-induced tumor necrosis factor receptor-related protein (GITR) and GITR ligand (GITRL) regulate immune cell activities, including anti-tumor immune responses. Structures and visualization of human and mouse GITR–GITRL complexes offer insight into the architecture of higher-order membra...
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Bibliographic Details
| Main Authors: |
Feng Wang,
Bryant Chau,
Sean M. West,
Christopher R. Kimberlin,
Fei Cao,
Flavio Schwarz,
Barbara Aguilar,
Minhua Han,
Winse Morishige,
Christine Bee,
Gavin Dollinger,
Arvind Rajpal,
Pavel Strop |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2021-03-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-021-21563-z
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