Anemia and The Level of IL-6 in Children Infected with Entamoeba histolytica and Giardia lamblia

The relation between anemia and inflammatory immune response has lately had much attention. This research was conducted from October 2018 until April 2019, including  (110) children below 12 years from both gender in some Hospitals, Primary Health care centers, Public Primary Schools and Kindergarte...

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Main Authors: Israa N. Zeki, Harith Saeed Al-Warid
Format: Article
Language:Arabic
Published: College of Science for Women, University of Baghdad 2021-12-01
Series:Baghdad Science Journal
Subjects:
Online Access:https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/5314
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author Israa N. Zeki
Harith Saeed Al-Warid
author_facet Israa N. Zeki
Harith Saeed Al-Warid
author_sort Israa N. Zeki
collection DOAJ
description The relation between anemia and inflammatory immune response has lately had much attention. This research was conducted from October 2018 until April 2019, including  (110) children below 12 years from both gender in some Hospitals, Primary Health care centers, Public Primary Schools and Kindergarten in Baghdad, Iraq. The objective of this study is to determine the possible correlation between iron deficiency anemia and inflammatory immune response  among children infected with Entamoeba  histolytica or Giardia  lamblia. Blood samples were taken from all groups to measure  hemoglobin level, serum iron, total iron binding capacity (TIBC), mean corpuscular volume (MCV), and mean corpuscular  hemoglobin concentration (MCHC), while the inflammatory related immune response was evaluated by measuring IL-6 and ferritin. Student T-Test was used to compare between means. The results  showed that both  hemoglobin and iron concentrations were significantly (P) ˂ 0.01 lower in infected children compared with control, as well as both IL-6 and ferritin levels were significant where (P) ˂0.05 amplified among infected children compared to control. Microcytic hypochromic anemia was observed in the majority of infected children, while normocytic normochromic RBCs was recorded in the majority of control children.
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spelling doaj.art-339bee5a89cc48a787ed2fcf104e9a302022-12-21T20:12:39ZaraCollege of Science for Women, University of BaghdadBaghdad Science Journal2078-86652411-79862021-12-01184(Suppl.)10.21123/bsj.2021.18.4(Suppl.).1485Anemia and The Level of IL-6 in Children Infected with Entamoeba histolytica and Giardia lambliaIsraa N. Zeki0Harith Saeed Al-Warid1Central Organization for Standardization and Quality Control Baghdad, IraqDepartment of Biology, College of Science, University of Baghdad, Baghdad, Iraq.The relation between anemia and inflammatory immune response has lately had much attention. This research was conducted from October 2018 until April 2019, including  (110) children below 12 years from both gender in some Hospitals, Primary Health care centers, Public Primary Schools and Kindergarten in Baghdad, Iraq. The objective of this study is to determine the possible correlation between iron deficiency anemia and inflammatory immune response  among children infected with Entamoeba  histolytica or Giardia  lamblia. Blood samples were taken from all groups to measure  hemoglobin level, serum iron, total iron binding capacity (TIBC), mean corpuscular volume (MCV), and mean corpuscular  hemoglobin concentration (MCHC), while the inflammatory related immune response was evaluated by measuring IL-6 and ferritin. Student T-Test was used to compare between means. The results  showed that both  hemoglobin and iron concentrations were significantly (P) ˂ 0.01 lower in infected children compared with control, as well as both IL-6 and ferritin levels were significant where (P) ˂0.05 amplified among infected children compared to control. Microcytic hypochromic anemia was observed in the majority of infected children, while normocytic normochromic RBCs was recorded in the majority of control children.https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/5314Children, E. histolytica, G lamblia, , IL-6, microcytic anemia
spellingShingle Israa N. Zeki
Harith Saeed Al-Warid
Anemia and The Level of IL-6 in Children Infected with Entamoeba histolytica and Giardia lamblia
Baghdad Science Journal
Children, E. histolytica, G lamblia, , IL-6, microcytic anemia
title Anemia and The Level of IL-6 in Children Infected with Entamoeba histolytica and Giardia lamblia
title_full Anemia and The Level of IL-6 in Children Infected with Entamoeba histolytica and Giardia lamblia
title_fullStr Anemia and The Level of IL-6 in Children Infected with Entamoeba histolytica and Giardia lamblia
title_full_unstemmed Anemia and The Level of IL-6 in Children Infected with Entamoeba histolytica and Giardia lamblia
title_short Anemia and The Level of IL-6 in Children Infected with Entamoeba histolytica and Giardia lamblia
title_sort anemia and the level of il 6 in children infected with entamoeba histolytica and giardia lamblia
topic Children, E. histolytica, G lamblia, , IL-6, microcytic anemia
url https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/5314
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AT harithsaeedalwarid anemiaandthelevelofil6inchildreninfectedwithentamoebahistolyticaandgiardialamblia