Thermal Physics and Glaucoma: From Thermodynamic to Biophysical Considerations to Designing Future Therapies
This paper presents a theoretical approach to glaucoma, with the aim of improving the comprehension of the biophysical bases for new possible therapies. The approach is based on a non-equilibrium thermodynamic model. The results point to the fundamental role of the membrane’s electric potential and...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-10-01
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| Series: | Applied Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3417/10/20/7071 |
| _version_ | 1797551269051629568 |
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| author | Umberto Lucia Giulia Grisolia |
| author_facet | Umberto Lucia Giulia Grisolia |
| author_sort | Umberto Lucia |
| collection | DOAJ |
| description | This paper presents a theoretical approach to glaucoma, with the aim of improving the comprehension of the biophysical bases for new possible therapies. The approach is based on a non-equilibrium thermodynamic model. The results point to the fundamental role of the membrane’s electric potential and of its relation with inflammation and ion fluxes. A new viewpoint is suggested to consider anti-inflammation and photobiomodulation as possible therapies for glaucoma. |
| first_indexed | 2024-03-10T15:42:11Z |
| format | Article |
| id | doaj.art-33a088bfa42e4b1a9b7530ed69030e51 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-10T15:42:11Z |
| publishDate | 2020-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-33a088bfa42e4b1a9b7530ed69030e512023-11-20T16:41:33ZengMDPI AGApplied Sciences2076-34172020-10-011020707110.3390/app10207071Thermal Physics and Glaucoma: From Thermodynamic to Biophysical Considerations to Designing Future TherapiesUmberto Lucia0Giulia Grisolia1Dipartimento Energia “Galileo Ferraris”, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, ItalyDipartimento Energia “Galileo Ferraris”, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, ItalyThis paper presents a theoretical approach to glaucoma, with the aim of improving the comprehension of the biophysical bases for new possible therapies. The approach is based on a non-equilibrium thermodynamic model. The results point to the fundamental role of the membrane’s electric potential and of its relation with inflammation and ion fluxes. A new viewpoint is suggested to consider anti-inflammation and photobiomodulation as possible therapies for glaucoma.https://www.mdpi.com/2076-3417/10/20/7071biophysicsglaucomanon-equilibrium thermodynamicsions fluxestransport theorythermodynamics of bio-systems |
| spellingShingle | Umberto Lucia Giulia Grisolia Thermal Physics and Glaucoma: From Thermodynamic to Biophysical Considerations to Designing Future Therapies Applied Sciences biophysics glaucoma non-equilibrium thermodynamics ions fluxes transport theory thermodynamics of bio-systems |
| title | Thermal Physics and Glaucoma: From Thermodynamic to Biophysical Considerations to Designing Future Therapies |
| title_full | Thermal Physics and Glaucoma: From Thermodynamic to Biophysical Considerations to Designing Future Therapies |
| title_fullStr | Thermal Physics and Glaucoma: From Thermodynamic to Biophysical Considerations to Designing Future Therapies |
| title_full_unstemmed | Thermal Physics and Glaucoma: From Thermodynamic to Biophysical Considerations to Designing Future Therapies |
| title_short | Thermal Physics and Glaucoma: From Thermodynamic to Biophysical Considerations to Designing Future Therapies |
| title_sort | thermal physics and glaucoma from thermodynamic to biophysical considerations to designing future therapies |
| topic | biophysics glaucoma non-equilibrium thermodynamics ions fluxes transport theory thermodynamics of bio-systems |
| url | https://www.mdpi.com/2076-3417/10/20/7071 |
| work_keys_str_mv | AT umbertolucia thermalphysicsandglaucomafromthermodynamictobiophysicalconsiderationstodesigningfuturetherapies AT giuliagrisolia thermalphysicsandglaucomafromthermodynamictobiophysicalconsiderationstodesigningfuturetherapies |