The Multifunctional Protein Syntenin-1: Regulator of Exosome Biogenesis, Cellular Function, and Tumor Progression
Syntenin acts as an adaptor and scaffold protein through its two PSD-95, Dlg, and ZO-1 (PDZ) domains, participating in multiple signaling pathways and modulating cellular physiology. It has been identified as an oncogene, promoting cancer development, metastasis, and angiogenesis in various carcinom...
Main Authors: | Kwang-Min Lee, Eun-Chan Seo, Jeong-Hyung Lee, Hyo-Jin Kim, Cheol Hwangbo |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-05-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/24/11/9418 |
Similar Items
-
Anaplasma phagocytophilum Ats-1 enhances exosome secretion through Syntenin-1
by: Ruirui Li, et al.
Published: (2023-09-01) -
Alcohol Promotes Exosome Biogenesis and Release via Modulating Rabs and miR-192 Expression in Human Hepatocytes
by: Shashi Bala, et al.
Published: (2022-01-01) -
Downregulation of stromal syntenin sustains AML development
by: Raphael Leblanc, et al.
Published: (2023-11-01) -
Syntenin overexpression in human lung cancer tissue and serum is associated with poor prognosis
by: Pengyong Luo, et al.
Published: (2020-02-01) -
Biological Role and Aberrant Overexpression of Syntenin-1 in Cancer: Potential Role as a Biomarker and Therapeutic Target
by: Valeria Guadalupe Pintor-Romero, et al.
Published: (2023-03-01)