HIV-1 drug resistance emergence among breastfeeding infants born to HIV-infected mothers during a single-arm trial of triple-antiretroviral prophylaxis for prevention of mother-to-child transmission: a secondary analysis.

HIV-1 drug resistance emergence among breastfeeding infants born to HIV-infected mothers during a single-arm trial of triple-antiretroviral prophylaxis for prevention of mother-to-child transmission: a secondary analysis.

Nevirapine and lamivudine given to mothers are transmitted to infants via breastfeeding in quantities sufficient to have biologic effects on the virus; this may lead to an increased risk of a breastfed infant's development of resistance to maternal antiretrovirals. The Kisumu Breastfeeding Stud...

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Bibliographic Details
Main Authors: Clement Zeh, Paul J Weidle, Lillian Nafisa, Humphrey M Lwamba, Jully Okonji, Emily Anyango, Philip Bondo, Rose Masaba, Mary Glenn Fowler, John N Nkengasong, Michael C Thigpen, Timothy Thomas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC3066134?pdf=render

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