Prokaryotic expression of human-sourced and zebrafish-sourced protein kinase A alpha catalytic subunits combined with in vitro and in silico assay

Prokaryotic expression of human-sourced and zebrafish-sourced protein kinase A alpha catalytic subunits combined with in vitro and in silico assay

The extensively studied cAMP-dependent protein kinase A (PKA) is involved in the regulation of critical cell processes, including metabolism, gene expression, and cell proliferation. Therefore, PKA has been viewed increasingly as potential target for variety of drugs and environmental endocrine disr...

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Bibliographic Details
Main Authors: Kun Qiao, Yao Jiang, Tiantian Hu, Shuying Li, Wenjun Gui
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Protein kinase A alpha catalytic subunit
Prokaryotic expression
in vitro kinase activity detection
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651321011350

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