Investigating Chemokine-Matrix Networks in Breast Cancer: Tenascin-C Sets the Tone for CCL2

Investigating Chemokine-Matrix Networks in Breast Cancer: Tenascin-C Sets the Tone for CCL2

Bidirectional dialogue between cellular and non-cellular components of the tumor microenvironment (TME) drives cancer survival. In the extracellular space, combinations of matrix molecules and soluble mediators provide external cues that dictate the behavior of TME resident cells. Often studied in i...

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Bibliographic Details
Main Authors: Martha Gschwandtner, Anís N. Gammage, Claire Deligne, Linda F. M. Mies, Alissa Domaingo, Devardarssen Murdamoothoo, Thomas Loustau, Anja Schwenzer, Rupert Derler, Raphael Carapito, Manuel Koch, Matthias Mörgelin, Gertraud Orend, Andreas J. Kungl, Kim S. Midwood
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
CCL2
MCP-1
tenascin-C
extracellular matrix
breast cancer
myeloid cells
Online Access:https://www.mdpi.com/1422-0067/24/9/8365

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