Experimental Basis for the High Oral Toxicity of Dinophysistoxin 1: A Comparative Study of DSP

Experimental Basis for the High Oral Toxicity of Dinophysistoxin 1: A Comparative Study of DSP

Okadaic acid (OA) and its analogues, dinophysistoxin 1 (DTX1) and dinophysistoxin 2 (DTX2), are lipophilic and heat-stable marine toxins produced by dinoflagellates, which can accumulate in filter-feeding bivalves. These toxins cause diarrheic shellfish poisoning (DSP) in humans shortly after the in...

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Bibliographic Details
Main Authors:	Diego A. Fernández, M. Carmen Louzao, María Fraga, Natalia Vilariño, Mercedes R. Vieytes, Luis M. Botana
Format:	Article
Language:	English
Published:	MDPI AG 2014-01-01
Series:	Toxins
Subjects:	okadaic acid dinophysistoxin-1 dinophysistoxin-2 Caco-2 intestinal permeability trans-epithelial electric resistance occludin annexin V Luminex immunoassay
Online Access:	http://www.mdpi.com/2072-6651/6/1/211

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