ANTIBACTERIAL ACTIVITY OF RED PIGMENT ISOLATED FROM COASTAL ENDOPHYTIC FUNGI AGAINST MULTI-DRUG RESISTANT BACTERIA
Multidrug-resistant (MDR) bacteria infections become a serious problem for these several decades. To solve this issue, finding of new antibiotics candidate in an urgency. Natural pigment is known to has biological activity against pathogenic bacteria. Coastal fungi are unexplored source of natural p...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SEAMEO, BIOTROP
2017-08-01
|
| Series: | Biotropia: The Southeast Asian Journal of Tropical Biology |
| Subjects: | |
| Online Access: | https://journal.biotrop.org/index.php/biotropia/article/view/725 |
| _version_ | 1797781983061868544 |
|---|---|
| author | Mada Triandala Sibero Rita Sahara Nur Syafiqoh Kustiariyah Tarman |
| author_facet | Mada Triandala Sibero Rita Sahara Nur Syafiqoh Kustiariyah Tarman |
| author_sort | Mada Triandala Sibero |
| collection | DOAJ |
| description | Multidrug-resistant (MDR) bacteria infections become a serious problem for these several decades. To solve this issue, finding of new antibiotics candidate in an urgency. Natural pigment is known to has biological activity against pathogenic bacteria. Coastal fungi are unexplored source of natural pigment to fight MDR bacteria. This research was aimed to isolate coastal endophytic fungi from smooth ant plant (Hydophytum formicarum), to screen endophytic fungi which produce red pigment, to extract the red pigment, to determine antibacterial activity of the red pigment and to identify the coastal endophytic fungi producing the red pigment. In this study, 7 fungi were isolated as endophytic fungi from H. formicarum. There were 3 isolates which produced extracellular pigment i.e. RS 1A which produced red pigment, RS 3 produced black pigment and RS 6A produced yellow pigment. Our study focused on red pigment which is produced by endophytic fungus strain RS 1A. The yield of red pigment was 8.8657% (w/w). This study showed that red pigment had antibacterial activity against Escherichia coli, Acinetobacter baumannii and Proteus mirabilis strain MDR. Judging from molecular and morphological identification, the endophytic fungus strain RS 1A was identified as Aspergillus versicolor. |
| first_indexed | 2024-03-13T00:04:38Z |
| format | Article |
| id | doaj.art-33b06a847485488bbb5063d852cc5a9a |
| institution | Directory Open Access Journal |
| issn | 0215-6334 1907-770X |
| language | English |
| last_indexed | 2024-03-13T00:04:38Z |
| publishDate | 2017-08-01 |
| publisher | SEAMEO, BIOTROP |
| record_format | Article |
| series | Biotropia: The Southeast Asian Journal of Tropical Biology |
| spelling | doaj.art-33b06a847485488bbb5063d852cc5a9a2023-07-13T04:52:53ZengSEAMEO, BIOTROPBiotropia: The Southeast Asian Journal of Tropical Biology0215-63341907-770X2017-08-0124210.11598/btb.2017.24.2.725ANTIBACTERIAL ACTIVITY OF RED PIGMENT ISOLATED FROM COASTAL ENDOPHYTIC FUNGI AGAINST MULTI-DRUG RESISTANT BACTERIAMada Triandala Sibero0Rita Sahara1Nur Syafiqoh2Kustiariyah Tarman3Faculty of Fisheries and Marine Science, Diponegoro University, Tembalang, Semarang, Central Java, IndonesiaDepartment of Aquatic Products Technology, Faculty of Fisheries and Marine Science, Bogor Agricultural University, St. Agatis-FPIK Building, Dramaga, Bogor, West Java, IndonesiaDepartment of Microbiology, Faculty of Mathemeatic and Natural Sciences, Bogor Agricultural University, Dramaga, Bogor, West Java, IndonesiaDepartment of Aquatic Products Technology, Faculty of Fisheries and Marine Science, Bogor Agricultural University, St. Agatis-FPIK Building, Dramaga, Bogor, West Java, IndonesiaMultidrug-resistant (MDR) bacteria infections become a serious problem for these several decades. To solve this issue, finding of new antibiotics candidate in an urgency. Natural pigment is known to has biological activity against pathogenic bacteria. Coastal fungi are unexplored source of natural pigment to fight MDR bacteria. This research was aimed to isolate coastal endophytic fungi from smooth ant plant (Hydophytum formicarum), to screen endophytic fungi which produce red pigment, to extract the red pigment, to determine antibacterial activity of the red pigment and to identify the coastal endophytic fungi producing the red pigment. In this study, 7 fungi were isolated as endophytic fungi from H. formicarum. There were 3 isolates which produced extracellular pigment i.e. RS 1A which produced red pigment, RS 3 produced black pigment and RS 6A produced yellow pigment. Our study focused on red pigment which is produced by endophytic fungus strain RS 1A. The yield of red pigment was 8.8657% (w/w). This study showed that red pigment had antibacterial activity against Escherichia coli, Acinetobacter baumannii and Proteus mirabilis strain MDR. Judging from molecular and morphological identification, the endophytic fungus strain RS 1A was identified as Aspergillus versicolor.https://journal.biotrop.org/index.php/biotropia/article/view/725Antibacterialendophytic fungiMDRpigment |
| spellingShingle | Mada Triandala Sibero Rita Sahara Nur Syafiqoh Kustiariyah Tarman ANTIBACTERIAL ACTIVITY OF RED PIGMENT ISOLATED FROM COASTAL ENDOPHYTIC FUNGI AGAINST MULTI-DRUG RESISTANT BACTERIA Biotropia: The Southeast Asian Journal of Tropical Biology Antibacterial endophytic fungi MDR pigment |
| title | ANTIBACTERIAL ACTIVITY OF RED PIGMENT ISOLATED FROM COASTAL ENDOPHYTIC FUNGI AGAINST MULTI-DRUG RESISTANT BACTERIA |
| title_full | ANTIBACTERIAL ACTIVITY OF RED PIGMENT ISOLATED FROM COASTAL ENDOPHYTIC FUNGI AGAINST MULTI-DRUG RESISTANT BACTERIA |
| title_fullStr | ANTIBACTERIAL ACTIVITY OF RED PIGMENT ISOLATED FROM COASTAL ENDOPHYTIC FUNGI AGAINST MULTI-DRUG RESISTANT BACTERIA |
| title_full_unstemmed | ANTIBACTERIAL ACTIVITY OF RED PIGMENT ISOLATED FROM COASTAL ENDOPHYTIC FUNGI AGAINST MULTI-DRUG RESISTANT BACTERIA |
| title_short | ANTIBACTERIAL ACTIVITY OF RED PIGMENT ISOLATED FROM COASTAL ENDOPHYTIC FUNGI AGAINST MULTI-DRUG RESISTANT BACTERIA |
| title_sort | antibacterial activity of red pigment isolated from coastal endophytic fungi against multi drug resistant bacteria |
| topic | Antibacterial endophytic fungi MDR pigment |
| url | https://journal.biotrop.org/index.php/biotropia/article/view/725 |
| work_keys_str_mv | AT madatriandalasibero antibacterialactivityofredpigmentisolatedfromcoastalendophyticfungiagainstmultidrugresistantbacteria AT ritasahara antibacterialactivityofredpigmentisolatedfromcoastalendophyticfungiagainstmultidrugresistantbacteria AT nursyafiqoh antibacterialactivityofredpigmentisolatedfromcoastalendophyticfungiagainstmultidrugresistantbacteria AT kustiariyahtarman antibacterialactivityofredpigmentisolatedfromcoastalendophyticfungiagainstmultidrugresistantbacteria |