Dietary risk of neonicotinoid insecticides through fruit and vegetable consumption in school-age children
Although the systemic property of neonicotinoid (neonics) has become the most widely used insecticide worldwide since late 1990s, the current literature offers limited information about the human dietary intake and the potential risks of neonics. In this study, we aimed to assess the cumulative risk...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2019-05-01
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| Series: | Environment International |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0160412018327600 |
| _version_ | 1818536852071645184 |
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| author | Quan Zhang Zhengbiao Lu Chi-Hsuan Chang Chang Yu Ximing Wang Chensheng Lu |
| author_facet | Quan Zhang Zhengbiao Lu Chi-Hsuan Chang Chang Yu Ximing Wang Chensheng Lu |
| author_sort | Quan Zhang |
| collection | DOAJ |
| description | Although the systemic property of neonicotinoid (neonics) has become the most widely used insecticide worldwide since late 1990s, the current literature offers limited information about the human dietary intake and the potential risks of neonics. In this study, we aimed to assess the cumulative risk of total neonics intakes through fruit and vegetable consumption in 58 children ages 8–12 participated in the Hangzhou China (HZC) study over 5 consecutive weekends. Individual neonic residues in each food item were aggregated using the relative potency factor approach into a single metric (IMIRPF), representing dietary intakes of imidacloprid-equivalent total neonics. We then estimated the average daily intake (ADI) of total neonics through fruit and vegetable consumption and evaluated the cumulative dietary risk of neonics. All of the 123 samples were detected with at least one neonic. Commonly consumed foods, such as carrots, green vegetables, baby cabbage, and apple were found with more than 6 neonics. The estimated ADIs of total neonics vegetable and fruit consumption using the mean IMIRPF for apples and green vegetables, two most consumed food items, were 237.1*10−6 and 106.8*10−6 mg/kg/day, respectively. Although the estimated ADIs were below the current chronic reference dose (cRfD) of imidacloprid, we have stipulated the possible future downward revision of cRfD. The potential health risk of neonics to children via dietary exposure should raise more public concern considering the increase use of neonics and the ubiquitous presence in fruits and vegetables. Keywords: Neonicotinoids, Dietary intake, Cumulative dietary risk, Relative potency factor, Reference dose |
| first_indexed | 2024-12-11T18:43:16Z |
| format | Article |
| id | doaj.art-33b15d4694444eafa50710ece7897848 |
| institution | Directory Open Access Journal |
| issn | 0160-4120 |
| language | English |
| last_indexed | 2024-12-11T18:43:16Z |
| publishDate | 2019-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Environment International |
| spelling | doaj.art-33b15d4694444eafa50710ece78978482022-12-22T00:54:32ZengElsevierEnvironment International0160-41202019-05-01126672681Dietary risk of neonicotinoid insecticides through fruit and vegetable consumption in school-age childrenQuan Zhang0Zhengbiao Lu1Chi-Hsuan Chang2Chang Yu3Ximing Wang4Chensheng Lu5Key Laboratory of Microbial Technology for Industrial Pollution Control of Zhejiang Province, College of Environment, Zhejiang University of Technology, Hangzhou, Zhejiang 310032, People's Republic of China; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA 02115, United StatesKey Laboratory of Microbial Technology for Industrial Pollution Control of Zhejiang Province, College of Environment, Zhejiang University of Technology, Hangzhou, Zhejiang 310032, People's Republic of ChinaDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA 02115, United StatesKey Laboratory of Microbial Technology for Industrial Pollution Control of Zhejiang Province, College of Environment, Zhejiang University of Technology, Hangzhou, Zhejiang 310032, People's Republic of ChinaKey Laboratory of Microbial Technology for Industrial Pollution Control of Zhejiang Province, College of Environment, Zhejiang University of Technology, Hangzhou, Zhejiang 310032, People's Republic of ChinaCollege of Resources and Environment, Southwest University, Chongqing 400715, People's Republic of China; Corresponding author at: 2 Tiansheng Road, Beibei District, Chongqing, 400715, People's Republic of China.Although the systemic property of neonicotinoid (neonics) has become the most widely used insecticide worldwide since late 1990s, the current literature offers limited information about the human dietary intake and the potential risks of neonics. In this study, we aimed to assess the cumulative risk of total neonics intakes through fruit and vegetable consumption in 58 children ages 8–12 participated in the Hangzhou China (HZC) study over 5 consecutive weekends. Individual neonic residues in each food item were aggregated using the relative potency factor approach into a single metric (IMIRPF), representing dietary intakes of imidacloprid-equivalent total neonics. We then estimated the average daily intake (ADI) of total neonics through fruit and vegetable consumption and evaluated the cumulative dietary risk of neonics. All of the 123 samples were detected with at least one neonic. Commonly consumed foods, such as carrots, green vegetables, baby cabbage, and apple were found with more than 6 neonics. The estimated ADIs of total neonics vegetable and fruit consumption using the mean IMIRPF for apples and green vegetables, two most consumed food items, were 237.1*10−6 and 106.8*10−6 mg/kg/day, respectively. Although the estimated ADIs were below the current chronic reference dose (cRfD) of imidacloprid, we have stipulated the possible future downward revision of cRfD. The potential health risk of neonics to children via dietary exposure should raise more public concern considering the increase use of neonics and the ubiquitous presence in fruits and vegetables. Keywords: Neonicotinoids, Dietary intake, Cumulative dietary risk, Relative potency factor, Reference dosehttp://www.sciencedirect.com/science/article/pii/S0160412018327600 |
| spellingShingle | Quan Zhang Zhengbiao Lu Chi-Hsuan Chang Chang Yu Ximing Wang Chensheng Lu Dietary risk of neonicotinoid insecticides through fruit and vegetable consumption in school-age children Environment International |
| title | Dietary risk of neonicotinoid insecticides through fruit and vegetable consumption in school-age children |
| title_full | Dietary risk of neonicotinoid insecticides through fruit and vegetable consumption in school-age children |
| title_fullStr | Dietary risk of neonicotinoid insecticides through fruit and vegetable consumption in school-age children |
| title_full_unstemmed | Dietary risk of neonicotinoid insecticides through fruit and vegetable consumption in school-age children |
| title_short | Dietary risk of neonicotinoid insecticides through fruit and vegetable consumption in school-age children |
| title_sort | dietary risk of neonicotinoid insecticides through fruit and vegetable consumption in school age children |
| url | http://www.sciencedirect.com/science/article/pii/S0160412018327600 |
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