Examination of Processes of Cultivation of <i>V. cholerae</i> strains - Producers of Protective Antigens of Cholera Bivalent Chemical Vaccine in Tablets - in the Engineered Bioreactor
Studied is the kinetics of major antigen accumulation at growing of Vibrio cholerae M-41 Ogawa and 569 B Inaba strains in industrial and engineered reactors. Demonstrated is the possibility to obtain conditional native protective antigens in the engineered bioreactor. Shown is the identity of physio...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe”
2012-04-01
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| Series: | Проблемы особо опасных инфекций |
| Subjects: | |
| Online Access: | https://journal.microbe.ru/jour/article/view/804 |
| _version_ | 1797220931400105984 |
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| author | A. K. Nikiforov A. V. Komissarov A. Yu. Ul'yanov S. A. Eremin O. A. Volokh N. I. Belyakova Yu. A. Aleshina Yu. G. Vasin |
| author_facet | A. K. Nikiforov A. V. Komissarov A. Yu. Ul'yanov S. A. Eremin O. A. Volokh N. I. Belyakova Yu. A. Aleshina Yu. G. Vasin |
| author_sort | A. K. Nikiforov |
| collection | DOAJ |
| description | Studied is the kinetics of major antigen accumulation at growing of Vibrio cholerae M-41 Ogawa and 569 B Inaba strains in industrial and engineered reactors. Demonstrated is the possibility to obtain conditional native protective antigens in the engineered bioreactor. Shown is the identity of physiological and morphological properties of industrial Vibrio cholerae strains during their submerged cultivation in industrial and engineered bioreactors. Cholera bivalent chemical vaccine obtained using engineered bioreactor possesses quality indices meeting the requirements of normative documents and equal to those of preparation received by traditional approach. |
| first_indexed | 2024-03-08T13:44:14Z |
| format | Article |
| id | doaj.art-33b1c08435f94b6b9418b884fa30fc57 |
| institution | Directory Open Access Journal |
| issn | 0370-1069 2658-719X |
| language | Russian |
| last_indexed | 2024-04-24T12:57:23Z |
| publishDate | 2012-04-01 |
| publisher | Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” |
| record_format | Article |
| series | Проблемы особо опасных инфекций |
| spelling | doaj.art-33b1c08435f94b6b9418b884fa30fc572024-04-05T16:47:08ZrusFederal Government Health Institution, Russian Research Anti-Plague Institute “Microbe”Проблемы особо опасных инфекций0370-10692658-719X2012-04-0102(112)858810.21055/0370-1069-2012-2(112)-85-88788Examination of Processes of Cultivation of <i>V. cholerae</i> strains - Producers of Protective Antigens of Cholera Bivalent Chemical Vaccine in Tablets - in the Engineered BioreactorA. K. Nikiforov0A. V. Komissarov1A. Yu. Ul'yanov2S. A. Eremin3O. A. Volokh4N. I. Belyakova5Yu. A. Aleshina6Yu. G. Vasin7Russian Research Anti-Plague Institute MicrobeRussian Research Anti-Plague Institute MicrobeRussian Research Anti-Plague Institute MicrobeRussian Research Anti-Plague Institute MicrobeRussian Research Anti-Plague Institute MicrobeRussian Research Anti-Plague Institute MicrobeRussian Research Anti-Plague Institute MicrobeRussian Research Anti-Plague Institute MicrobeStudied is the kinetics of major antigen accumulation at growing of Vibrio cholerae M-41 Ogawa and 569 B Inaba strains in industrial and engineered reactors. Demonstrated is the possibility to obtain conditional native protective antigens in the engineered bioreactor. Shown is the identity of physiological and morphological properties of industrial Vibrio cholerae strains during their submerged cultivation in industrial and engineered bioreactors. Cholera bivalent chemical vaccine obtained using engineered bioreactor possesses quality indices meeting the requirements of normative documents and equal to those of preparation received by traditional approach.https://journal.microbe.ru/jour/article/view/804<i>vibrio cholerae</i>cholera vaccinecholeragen-anatoxino-antigencultivationproperties |
| spellingShingle | A. K. Nikiforov A. V. Komissarov A. Yu. Ul'yanov S. A. Eremin O. A. Volokh N. I. Belyakova Yu. A. Aleshina Yu. G. Vasin Examination of Processes of Cultivation of <i>V. cholerae</i> strains - Producers of Protective Antigens of Cholera Bivalent Chemical Vaccine in Tablets - in the Engineered Bioreactor Проблемы особо опасных инфекций <i>vibrio cholerae</i> cholera vaccine choleragen-anatoxin o-antigen cultivation properties |
| title | Examination of Processes of Cultivation of <i>V. cholerae</i> strains - Producers of Protective Antigens of Cholera Bivalent Chemical Vaccine in Tablets - in the Engineered Bioreactor |
| title_full | Examination of Processes of Cultivation of <i>V. cholerae</i> strains - Producers of Protective Antigens of Cholera Bivalent Chemical Vaccine in Tablets - in the Engineered Bioreactor |
| title_fullStr | Examination of Processes of Cultivation of <i>V. cholerae</i> strains - Producers of Protective Antigens of Cholera Bivalent Chemical Vaccine in Tablets - in the Engineered Bioreactor |
| title_full_unstemmed | Examination of Processes of Cultivation of <i>V. cholerae</i> strains - Producers of Protective Antigens of Cholera Bivalent Chemical Vaccine in Tablets - in the Engineered Bioreactor |
| title_short | Examination of Processes of Cultivation of <i>V. cholerae</i> strains - Producers of Protective Antigens of Cholera Bivalent Chemical Vaccine in Tablets - in the Engineered Bioreactor |
| title_sort | examination of processes of cultivation of i v cholerae i strains producers of protective antigens of cholera bivalent chemical vaccine in tablets in the engineered bioreactor |
| topic | <i>vibrio cholerae</i> cholera vaccine choleragen-anatoxin o-antigen cultivation properties |
| url | https://journal.microbe.ru/jour/article/view/804 |
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