Pathogenic <i>Leptospira</i> Infections in Hubei Province, Central China
Leptospirosis is an important zoonosis that is caused by pathogenic <i>Leptospira</i>, which is considered to be a re-emerging infectious disease in many countries. Rodents are the most important reservoirs for both human and animal infection. An epidemiological survey of pathogenic <...
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MDPI AG
2022-12-01
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| Series: | Microorganisms |
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| Online Access: | https://www.mdpi.com/2076-2607/11/1/99 |
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| author | Jiale Xu Jintao Chen Chaorui Xiong Lingxin Qin Bing Hu Manqing Liu Yuting Ren Yirong Li Kun Cai Liangjun Chen Wei Hou |
| author_facet | Jiale Xu Jintao Chen Chaorui Xiong Lingxin Qin Bing Hu Manqing Liu Yuting Ren Yirong Li Kun Cai Liangjun Chen Wei Hou |
| author_sort | Jiale Xu |
| collection | DOAJ |
| description | Leptospirosis is an important zoonosis that is caused by pathogenic <i>Leptospira</i>, which is considered to be a re-emerging infectious disease in many countries. Rodents are the most important reservoirs for both human and animal infection. An epidemiological survey of pathogenic <i>Leptospira</i> in rodents is important for the prevention and control of leptospirosis. In this study, a total of 964 rodents were captured from six cities in Hubei Province, and two pathogenic <i>Leptospira</i> species (<i>L. interrogans</i> and <i>L. borgpetersenii</i>) were detected using nested PCR with an overall prevalence of 4.8%. <i>L. interrogans</i> was distributed in five sampling sites, which may be the dominant species of pathogenic <i>Leptospira</i> in Hubei Province. In addition, <i>Rattus norvegicus</i> showed a relatively high infection rate, which may play an important role in the transmission and infection of pathogenic <i>Leptospira</i>. This study reveals the prevalence of pathogenic <i>Leptospira</i> in wild rodents in Hubei Province, suggesting that the risk of leptospirosis infection in Hubei Province still exists. |
| first_indexed | 2024-03-09T11:39:01Z |
| format | Article |
| id | doaj.art-33b5c2a2721a4abeade57c0ac4cf2283 |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-09T11:39:01Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-33b5c2a2721a4abeade57c0ac4cf22832023-11-30T23:36:24ZengMDPI AGMicroorganisms2076-26072022-12-011119910.3390/microorganisms11010099Pathogenic <i>Leptospira</i> Infections in Hubei Province, Central ChinaJiale Xu0Jintao Chen1Chaorui Xiong2Lingxin Qin3Bing Hu4Manqing Liu5Yuting Ren6Yirong Li7Kun Cai8Liangjun Chen9Wei Hou10State Key Laboratory of Virology/Department of Laboratory Medicine/Hubei Provincial Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Zhongnan Hospital, Wuhan University, 185 Donghu Road, Wuhan 430071, ChinaState Key Laboratory of Virology/Department of Laboratory Medicine/Hubei Provincial Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Zhongnan Hospital, Wuhan University, 185 Donghu Road, Wuhan 430071, ChinaState Key Laboratory of Virology/Department of Laboratory Medicine/Hubei Provincial Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Zhongnan Hospital, Wuhan University, 185 Donghu Road, Wuhan 430071, ChinaState Key Laboratory of Virology/Department of Laboratory Medicine/Hubei Provincial Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Zhongnan Hospital, Wuhan University, 185 Donghu Road, Wuhan 430071, ChinaInstitute of Health Inspection and Testing, Hubei Provincial Center for Disease Control & Prevention, 6 Zuodaoquan Road, Wuhan 430079, ChinaDivision of Virology, Wuhan Center for Disease Control & Prevention, 288 Machang Road, Wuhan 430015, ChinaState Key Laboratory of Virology/Department of Laboratory Medicine/Hubei Provincial Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Zhongnan Hospital, Wuhan University, 185 Donghu Road, Wuhan 430071, ChinaState Key Laboratory of Virology/Department of Laboratory Medicine/Hubei Provincial Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Zhongnan Hospital, Wuhan University, 185 Donghu Road, Wuhan 430071, ChinaInstitute of Health Inspection and Testing, Hubei Provincial Center for Disease Control & Prevention, 6 Zuodaoquan Road, Wuhan 430079, ChinaState Key Laboratory of Virology/Department of Laboratory Medicine/Hubei Provincial Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Zhongnan Hospital, Wuhan University, 185 Donghu Road, Wuhan 430071, ChinaState Key Laboratory of Virology/Department of Laboratory Medicine/Hubei Provincial Key Laboratory of Allergy and Immunology, School of Basic Medical Sciences, Zhongnan Hospital, Wuhan University, 185 Donghu Road, Wuhan 430071, ChinaLeptospirosis is an important zoonosis that is caused by pathogenic <i>Leptospira</i>, which is considered to be a re-emerging infectious disease in many countries. Rodents are the most important reservoirs for both human and animal infection. An epidemiological survey of pathogenic <i>Leptospira</i> in rodents is important for the prevention and control of leptospirosis. In this study, a total of 964 rodents were captured from six cities in Hubei Province, and two pathogenic <i>Leptospira</i> species (<i>L. interrogans</i> and <i>L. borgpetersenii</i>) were detected using nested PCR with an overall prevalence of 4.8%. <i>L. interrogans</i> was distributed in five sampling sites, which may be the dominant species of pathogenic <i>Leptospira</i> in Hubei Province. In addition, <i>Rattus norvegicus</i> showed a relatively high infection rate, which may play an important role in the transmission and infection of pathogenic <i>Leptospira</i>. This study reveals the prevalence of pathogenic <i>Leptospira</i> in wild rodents in Hubei Province, suggesting that the risk of leptospirosis infection in Hubei Province still exists.https://www.mdpi.com/2076-2607/11/1/99pathogenic <i>Leptospira</i>wild rodentzoonosiscentral China |
| spellingShingle | Jiale Xu Jintao Chen Chaorui Xiong Lingxin Qin Bing Hu Manqing Liu Yuting Ren Yirong Li Kun Cai Liangjun Chen Wei Hou Pathogenic <i>Leptospira</i> Infections in Hubei Province, Central China Microorganisms pathogenic <i>Leptospira</i> wild rodent zoonosis central China |
| title | Pathogenic <i>Leptospira</i> Infections in Hubei Province, Central China |
| title_full | Pathogenic <i>Leptospira</i> Infections in Hubei Province, Central China |
| title_fullStr | Pathogenic <i>Leptospira</i> Infections in Hubei Province, Central China |
| title_full_unstemmed | Pathogenic <i>Leptospira</i> Infections in Hubei Province, Central China |
| title_short | Pathogenic <i>Leptospira</i> Infections in Hubei Province, Central China |
| title_sort | pathogenic i leptospira i infections in hubei province central china |
| topic | pathogenic <i>Leptospira</i> wild rodent zoonosis central China |
| url | https://www.mdpi.com/2076-2607/11/1/99 |
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