Recent Advances in Bioengineered Scaffolds for Cutaneous Wound Healing
Wound healing is an evolved dynamic biological process. Though many research and clinical approaches have been explored to restore damaged or diseased skin, the current treatment for deep cutaneous injuries is far from being perfect, and the ideal regenerative therapy remains a significant challenge...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-03-01
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| Series: | Frontiers in Bioengineering and Biotechnology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2022.841583/full |
| _version_ | 1818982172130803712 |
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| author | Jianghui Qin Fang Chen Pingli Wu Guoming Sun |
| author_facet | Jianghui Qin Fang Chen Pingli Wu Guoming Sun |
| author_sort | Jianghui Qin |
| collection | DOAJ |
| description | Wound healing is an evolved dynamic biological process. Though many research and clinical approaches have been explored to restore damaged or diseased skin, the current treatment for deep cutaneous injuries is far from being perfect, and the ideal regenerative therapy remains a significant challenge. Of all treatments, bioengineered scaffolds play a key role and represent great progress in wound repair and skin regeneration. In this review, we focus on the latest advancement in biomaterial scaffolds for wound healing. We discuss the emerging philosophy of designing biomaterial scaffolds, followed by precursor development. We pay particular attention to the therapeutic interventions of bioengineered scaffolds for cutaneous wound healing, and their dual effects while conjugating with bioactive molecules, stem cells, and even immunomodulation. As we review the advancement and the challenges of the current strategies, we also discuss the prospects of scaffold development for wound healing. |
| first_indexed | 2024-12-20T17:42:59Z |
| format | Article |
| id | doaj.art-33b5d64a5b69402286774a08ca663eb2 |
| institution | Directory Open Access Journal |
| issn | 2296-4185 |
| language | English |
| last_indexed | 2024-12-20T17:42:59Z |
| publishDate | 2022-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj.art-33b5d64a5b69402286774a08ca663eb22022-12-21T19:31:03ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852022-03-011010.3389/fbioe.2022.841583841583Recent Advances in Bioengineered Scaffolds for Cutaneous Wound HealingJianghui Qin0Fang Chen1Pingli Wu2Guoming Sun3College of Chemistry and Environmental Science, Institute of Life Science and Green Development, Hebei University, Baoding, ChinaAffiliated Hospital of Hebei University, College of Clinical Medicine, Institute of Life Science and Green Development, Hebei University, Baoding, ChinaCollege of Chemistry and Environmental Science, Institute of Life Science and Green Development, Hebei University, Baoding, ChinaAffiliated Hospital of Hebei University, College of Clinical Medicine, Institute of Life Science and Green Development, Hebei University, Baoding, ChinaWound healing is an evolved dynamic biological process. Though many research and clinical approaches have been explored to restore damaged or diseased skin, the current treatment for deep cutaneous injuries is far from being perfect, and the ideal regenerative therapy remains a significant challenge. Of all treatments, bioengineered scaffolds play a key role and represent great progress in wound repair and skin regeneration. In this review, we focus on the latest advancement in biomaterial scaffolds for wound healing. We discuss the emerging philosophy of designing biomaterial scaffolds, followed by precursor development. We pay particular attention to the therapeutic interventions of bioengineered scaffolds for cutaneous wound healing, and their dual effects while conjugating with bioactive molecules, stem cells, and even immunomodulation. As we review the advancement and the challenges of the current strategies, we also discuss the prospects of scaffold development for wound healing.https://www.frontiersin.org/articles/10.3389/fbioe.2022.841583/fullbiomaterialswound healingskinbioengineered scaffoldspro-regenerative |
| spellingShingle | Jianghui Qin Fang Chen Pingli Wu Guoming Sun Recent Advances in Bioengineered Scaffolds for Cutaneous Wound Healing Frontiers in Bioengineering and Biotechnology biomaterials wound healing skin bioengineered scaffolds pro-regenerative |
| title | Recent Advances in Bioengineered Scaffolds for Cutaneous Wound Healing |
| title_full | Recent Advances in Bioengineered Scaffolds for Cutaneous Wound Healing |
| title_fullStr | Recent Advances in Bioengineered Scaffolds for Cutaneous Wound Healing |
| title_full_unstemmed | Recent Advances in Bioengineered Scaffolds for Cutaneous Wound Healing |
| title_short | Recent Advances in Bioengineered Scaffolds for Cutaneous Wound Healing |
| title_sort | recent advances in bioengineered scaffolds for cutaneous wound healing |
| topic | biomaterials wound healing skin bioengineered scaffolds pro-regenerative |
| url | https://www.frontiersin.org/articles/10.3389/fbioe.2022.841583/full |
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