Targeting pancreatic stellate cells in chronic pancreatitis: Focus on therapeutic drugs and natural compounds

Targeting pancreatic stellate cells in chronic pancreatitis: Focus on therapeutic drugs and natural compounds

Chronic pancreatitis (CP) is a precancerous illness linked to pancreatic ductal adenocarcinoma (PDAC), although the evolutionary mechanism is uncertain. CP is distinguished by severe fibrosis caused by the activation of pancreatic stellate cells (PSCs). The current clinical therapeutic protocol for...

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Bibliographic Details
Main Authors:	Yang Wu, Chun Zhang, Mei Guo, Weikang Hu, Yangling Qiu, Mengran Li, Dong Xu, Pengfei Wu, Jing Sun, Run Shi, Zili Zhang, Kuirong Jiang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-10-01
Series:	Frontiers in Pharmacology
Subjects:	CP PSCs natural compounds pancreatic fibrosis anti-fibrotic drug
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2022.1042651/full

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