Severe brain injury management

Management of severe brain injury, the main cause of death in young population, has now standardized principles that lead to the improving of the outcome. The treatment of this traumatic illness is directly connected to cerebral physiopathology. After the impact, there are some cerebral mechanisms t...

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Main Authors: Eva Gheorghita, Cristina Bucur, Luminita Neagoe, Jean Ciurea, Jemna Constantin
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2009-12-01
Series:Romanian Journal of Neurology
Subjects:
Online Access:https://rjn.com.ro/articles/2009.4/RJN_2009_4_Art-03.pdf
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author Eva Gheorghita
Cristina Bucur
Luminita Neagoe
Jean Ciurea
Jemna Constantin
author_facet Eva Gheorghita
Cristina Bucur
Luminita Neagoe
Jean Ciurea
Jemna Constantin
author_sort Eva Gheorghita
collection DOAJ
description Management of severe brain injury, the main cause of death in young population, has now standardized principles that lead to the improving of the outcome. The treatment of this traumatic illness is directly connected to cerebral physiopathology. After the impact, there are some cerebral mechanisms that are modified and are responsible for the appearance of the secondary injury: damaging of the cerebral metabolism, which has characteristic a very high metabolic rate compared to other tissues, altering the cerebral blood flow responsible for the cerebral oxygenation, altering the blood brain barrier with direct consequences on cerebral edema. Therefore, therapeutic aspects are connected to monitoring and will address to ensuring the hemodynamic stability, accurate oxygenation and correction of the factors that may worsen secondary injury (temperature, glycemia, osmolarity).
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spelling doaj.art-33bf60ecea8c4300a0fb563a3b3f5a242022-12-22T02:34:38ZengAmaltea Medical Publishing HouseRomanian Journal of Neurology1843-81482069-60942009-12-018416617310.37897/RJN.2009.4.3Severe brain injury managementEva Gheorghita0Cristina Bucur1Luminita Neagoe2Jean Ciurea3Jemna Constantin4“Bagdasar-Arseni” Emergency Hospital, Bucharest, Romania“Bagdasar-Arseni” Emergency Hospital, Bucharest, Romania“Bagdasar-Arseni” Emergency Hospital, Bucharest, Romania“Bagdasar-Arseni” Emergency Hospital, Bucharest, Romania“Bagdasar-Arseni” Emergency Hospital, Bucharest, RomaniaManagement of severe brain injury, the main cause of death in young population, has now standardized principles that lead to the improving of the outcome. The treatment of this traumatic illness is directly connected to cerebral physiopathology. After the impact, there are some cerebral mechanisms that are modified and are responsible for the appearance of the secondary injury: damaging of the cerebral metabolism, which has characteristic a very high metabolic rate compared to other tissues, altering the cerebral blood flow responsible for the cerebral oxygenation, altering the blood brain barrier with direct consequences on cerebral edema. Therefore, therapeutic aspects are connected to monitoring and will address to ensuring the hemodynamic stability, accurate oxygenation and correction of the factors that may worsen secondary injury (temperature, glycemia, osmolarity).https://rjn.com.ro/articles/2009.4/RJN_2009_4_Art-03.pdfbrain injurycerebral metabolismcerebral perfusion pressurevasogenic edemahypothermiaglycemiasodemia
spellingShingle Eva Gheorghita
Cristina Bucur
Luminita Neagoe
Jean Ciurea
Jemna Constantin
Severe brain injury management
Romanian Journal of Neurology
brain injury
cerebral metabolism
cerebral perfusion pressure
vasogenic edema
hypothermia
glycemia
sodemia
title Severe brain injury management
title_full Severe brain injury management
title_fullStr Severe brain injury management
title_full_unstemmed Severe brain injury management
title_short Severe brain injury management
title_sort severe brain injury management
topic brain injury
cerebral metabolism
cerebral perfusion pressure
vasogenic edema
hypothermia
glycemia
sodemia
url https://rjn.com.ro/articles/2009.4/RJN_2009_4_Art-03.pdf
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AT cristinabucur severebraininjurymanagement
AT luminitaneagoe severebraininjurymanagement
AT jeanciurea severebraininjurymanagement
AT jemnaconstantin severebraininjurymanagement