The association of dietary inflammatory potential with skeletal muscle strength, mass, and sarcopenia: a meta-analysis
AimsEvidence suggested that dietary inflammatory potential may be associated with age-related skeletal muscle decline, but the results remained controversial. To summarize the evidence for the relationships between dietary inflammatory potential and skeletal muscle strength, mass, and sarcopenia in...
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Frontiers Media S.A.
2023-05-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2023.1100918/full |
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| author | Haibin Xie Haochen Wang Ziying Wu Wei Li Yanzhe Liu Ning Wang Ning Wang Ning Wang Ning Wang |
| author_facet | Haibin Xie Haochen Wang Ziying Wu Wei Li Yanzhe Liu Ning Wang Ning Wang Ning Wang Ning Wang |
| author_sort | Haibin Xie |
| collection | DOAJ |
| description | AimsEvidence suggested that dietary inflammatory potential may be associated with age-related skeletal muscle decline, but the results remained controversial. To summarize the evidence for the relationships between dietary inflammatory potential and skeletal muscle strength, mass, and sarcopenia in adults we conducted this meta-analysis.MethodsEmbase, Pubmed, and Web of Science were searched from inception up to 12 March 2023 for studies that evaluated the associations of dietary inflammatory potential [estimated by the Dietary inflammatory index (DII)] with skeletal muscle strength, mass, and sarcopenia. A meta-analysis was then performed to calculate the pooled regression coefficient (β) and odds ratio (OR). The non-linear dose-response relation between DII and sarcopenia was assessed using random-effects dose-response meta-analysis.ResultsThis meta-analysis included 24 studies involving 56,536 participants. It was found that high DII was associated with low skeletal muscle strength [OR 1.435, 95% confidence interval (CI) 1.247–1.651, P < 0.001, I2 = 4.97%]. There was a negative association of DII with skeletal muscle strength (β−0.031, 95% CI −0.056 to −0.006, P = 0.017, I2 = 72.69%). High DII was also associated with low skeletal muscle mass (OR 1.106, 95% CI 1.058–1.157, P < 0.001, I2 = 0%). DII had a negative relationship with skeletal muscle mass with high heterogeneity (β−0.099, 95% CI −0.145 to −0.053, P < 0.001, I2 = 88.67%); we downgraded the inconsistency in the subgroup analysis of overweight/obese participants (β−0.042, 95% CI −0.065 to −0.019, I2 = 12.54%). Finally, the pooled results suggested that high DII was significantly associated with sarcopenia with significant heterogeneity (OR 1.530, 95% CI 1.245–1.880, P < 0.001, I2 = 69.46%); age and BMI may contribute partially to the heterogeneity since heterogeneity was decreased in the subgroup of older age (OR 1.939, 95% CI 1.232–3.051, I2 = 0%) and the group of overweight/obesity (OR 1.853, 95% CI 1.398–2.456, I2 = 0%). There was a non-linear dose-response association between DII and sarcopenia (P = 0.012 for non-linearity).ConclusionThis meta-analysis suggested that higher dietary inflammatory potential was significantly associated with lower skeletal muscle strength, mass, and risk of sarcopenia. Future studies with consistent assessment and standardized methodology are needed for further analysis. |
| first_indexed | 2024-04-09T12:38:25Z |
| format | Article |
| id | doaj.art-33bfaa48b9bd4a19894ffb2ab3d9c915 |
| institution | Directory Open Access Journal |
| issn | 2296-861X |
| language | English |
| last_indexed | 2024-04-09T12:38:25Z |
| publishDate | 2023-05-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Nutrition |
| spelling | doaj.art-33bfaa48b9bd4a19894ffb2ab3d9c9152023-05-15T04:40:47ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2023-05-011010.3389/fnut.2023.11009181100918The association of dietary inflammatory potential with skeletal muscle strength, mass, and sarcopenia: a meta-analysisHaibin Xie0Haochen Wang1Ziying Wu2Wei Li3Yanzhe Liu4Ning Wang5Ning Wang6Ning Wang7Ning Wang8Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, ChinaHunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital, Central South University, Changsha, ChinaNational Clinical Research Center of Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, ChinaKey Laboratory of Aging-Related Bone and Joint Diseases Prevention and Treatment, Ministry of Education, Xiangya Hospital, Central South University, Changsha, ChinaAimsEvidence suggested that dietary inflammatory potential may be associated with age-related skeletal muscle decline, but the results remained controversial. To summarize the evidence for the relationships between dietary inflammatory potential and skeletal muscle strength, mass, and sarcopenia in adults we conducted this meta-analysis.MethodsEmbase, Pubmed, and Web of Science were searched from inception up to 12 March 2023 for studies that evaluated the associations of dietary inflammatory potential [estimated by the Dietary inflammatory index (DII)] with skeletal muscle strength, mass, and sarcopenia. A meta-analysis was then performed to calculate the pooled regression coefficient (β) and odds ratio (OR). The non-linear dose-response relation between DII and sarcopenia was assessed using random-effects dose-response meta-analysis.ResultsThis meta-analysis included 24 studies involving 56,536 participants. It was found that high DII was associated with low skeletal muscle strength [OR 1.435, 95% confidence interval (CI) 1.247–1.651, P < 0.001, I2 = 4.97%]. There was a negative association of DII with skeletal muscle strength (β−0.031, 95% CI −0.056 to −0.006, P = 0.017, I2 = 72.69%). High DII was also associated with low skeletal muscle mass (OR 1.106, 95% CI 1.058–1.157, P < 0.001, I2 = 0%). DII had a negative relationship with skeletal muscle mass with high heterogeneity (β−0.099, 95% CI −0.145 to −0.053, P < 0.001, I2 = 88.67%); we downgraded the inconsistency in the subgroup analysis of overweight/obese participants (β−0.042, 95% CI −0.065 to −0.019, I2 = 12.54%). Finally, the pooled results suggested that high DII was significantly associated with sarcopenia with significant heterogeneity (OR 1.530, 95% CI 1.245–1.880, P < 0.001, I2 = 69.46%); age and BMI may contribute partially to the heterogeneity since heterogeneity was decreased in the subgroup of older age (OR 1.939, 95% CI 1.232–3.051, I2 = 0%) and the group of overweight/obesity (OR 1.853, 95% CI 1.398–2.456, I2 = 0%). There was a non-linear dose-response association between DII and sarcopenia (P = 0.012 for non-linearity).ConclusionThis meta-analysis suggested that higher dietary inflammatory potential was significantly associated with lower skeletal muscle strength, mass, and risk of sarcopenia. Future studies with consistent assessment and standardized methodology are needed for further analysis.https://www.frontiersin.org/articles/10.3389/fnut.2023.1100918/fulldietary inflammatory index (DII)sarcopeniamusclemeta-analysisnutrition |
| spellingShingle | Haibin Xie Haochen Wang Ziying Wu Wei Li Yanzhe Liu Ning Wang Ning Wang Ning Wang Ning Wang The association of dietary inflammatory potential with skeletal muscle strength, mass, and sarcopenia: a meta-analysis Frontiers in Nutrition dietary inflammatory index (DII) sarcopenia muscle meta-analysis nutrition |
| title | The association of dietary inflammatory potential with skeletal muscle strength, mass, and sarcopenia: a meta-analysis |
| title_full | The association of dietary inflammatory potential with skeletal muscle strength, mass, and sarcopenia: a meta-analysis |
| title_fullStr | The association of dietary inflammatory potential with skeletal muscle strength, mass, and sarcopenia: a meta-analysis |
| title_full_unstemmed | The association of dietary inflammatory potential with skeletal muscle strength, mass, and sarcopenia: a meta-analysis |
| title_short | The association of dietary inflammatory potential with skeletal muscle strength, mass, and sarcopenia: a meta-analysis |
| title_sort | association of dietary inflammatory potential with skeletal muscle strength mass and sarcopenia a meta analysis |
| topic | dietary inflammatory index (DII) sarcopenia muscle meta-analysis nutrition |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2023.1100918/full |
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