Platelet Inhibition by Low-Dose Acetylsalicylic Acid Reduces Neuroinflammation in an Animal Model of Multiple Sclerosis

Platelet Inhibition by Low-Dose Acetylsalicylic Acid Reduces Neuroinflammation in an Animal Model of Multiple Sclerosis

Aside from the established immune-mediated etiology of multiple sclerosis (MS), compelling evidence implicates platelets as important players in disease pathogenesis. Specifically, numerous studies have highlighted that activated platelets promote the central nervous system (CNS)-directed adaptive i...

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Bibliographic Details
Main Authors: Anna Vogelsang, Susann Eichler, Niklas Huntemann, Lars Masanneck, Hannes Böhnlein, Lisa Schüngel, Alice Willison, Karin Loser, Bernhard Nieswandt, Beate E. Kehrel, Alexander Zarbock, Kerstin Göbel, Sven G. Meuth
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
acetylsalicylic acid
experimental autoimmune encephalomyelitis
platelets
multiple sclerosis
thromboxane
glycoprotein VI
Online Access:https://www.mdpi.com/1422-0067/22/18/9915

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