insomniac links the development and function of a sleep-regulatory circuit

insomniac links the development and function of a sleep-regulatory circuit

Although many genes are known to influence sleep, when and how they impact sleep-regulatory circuits remain ill-defined. Here, we show that insomniac (inc), a conserved adaptor for the autism-associated Cul3 ubiquitin ligase, acts in a restricted period of neuronal development to impact sleep in adu...

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Bibliographic Details
Main Authors: Qiuling Li, Hyunsoo Jang, Kayla Y Lim, Alexie Lessing, Nicholas Stavropoulos
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-12-01
Series:eLife
Subjects:
neurogenesis
neuroblast
autism
neurodevelopmental disorders
Cul3
sleep disorders
Online Access:https://elifesciences.org/articles/65437

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