Recent Advances in Microfluidic Devices for Contamination Detection and Quality Inspection of Milk

Milk is a necessity for human life. However, it is susceptible to contamination and adulteration. Microfluidic analysis devices have attracted significant attention for the high-throughput quality inspection and contaminant analysis of milk samples in recent years. This review describes the major pr...

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Main Authors: Hwee-Yeong Ng, Wen-Chin Lee, Chia-Te Kung, Lung-Chih Li, Chien-Te Lee, Lung-Ming Fu
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Micromachines
Subjects:
Online Access:https://www.mdpi.com/2072-666X/12/5/558
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author Hwee-Yeong Ng
Wen-Chin Lee
Chia-Te Kung
Lung-Chih Li
Chien-Te Lee
Lung-Ming Fu
author_facet Hwee-Yeong Ng
Wen-Chin Lee
Chia-Te Kung
Lung-Chih Li
Chien-Te Lee
Lung-Ming Fu
author_sort Hwee-Yeong Ng
collection DOAJ
description Milk is a necessity for human life. However, it is susceptible to contamination and adulteration. Microfluidic analysis devices have attracted significant attention for the high-throughput quality inspection and contaminant analysis of milk samples in recent years. This review describes the major proposals presented in the literature for the pretreatment, contaminant detection, and quality inspection of milk samples using microfluidic lab-on-a-chip and lab-on-paper platforms in the past five years. The review focuses on the sample separation, sample extraction, and sample preconcentration/amplification steps of the pretreatment process and the determination of aflatoxins, antibiotics, drugs, melamine, and foodborne pathogens in the detection process. Recent proposals for the general quality inspection of milk samples, including the viscosity and presence of adulteration, are also discussed. The review concludes with a brief perspective on the challenges facing the future development of microfluidic devices for the analysis of milk samples in the coming years.
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spelling doaj.art-33c710c20c7f44dfb2056af4ecb613032023-11-21T19:43:24ZengMDPI AGMicromachines2072-666X2021-05-0112555810.3390/mi12050558Recent Advances in Microfluidic Devices for Contamination Detection and Quality Inspection of MilkHwee-Yeong Ng0Wen-Chin Lee1Chia-Te Kung2Lung-Chih Li3Chien-Te Lee4Lung-Ming Fu5Division of Nephrology, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung 833, TaiwanDivision of Nephrology, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung 833, TaiwanDepartment of Emergency Medicine, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung 833, TaiwanDivision of Nephrology, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung 833, TaiwanDivision of Nephrology, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung 833, TaiwanDepartment of Engineering Science, National Cheng Kung University, Tainan 701, TaiwanMilk is a necessity for human life. However, it is susceptible to contamination and adulteration. Microfluidic analysis devices have attracted significant attention for the high-throughput quality inspection and contaminant analysis of milk samples in recent years. This review describes the major proposals presented in the literature for the pretreatment, contaminant detection, and quality inspection of milk samples using microfluidic lab-on-a-chip and lab-on-paper platforms in the past five years. The review focuses on the sample separation, sample extraction, and sample preconcentration/amplification steps of the pretreatment process and the determination of aflatoxins, antibiotics, drugs, melamine, and foodborne pathogens in the detection process. Recent proposals for the general quality inspection of milk samples, including the viscosity and presence of adulteration, are also discussed. The review concludes with a brief perspective on the challenges facing the future development of microfluidic devices for the analysis of milk samples in the coming years.https://www.mdpi.com/2072-666X/12/5/558microfluidiclab-on-a-chiplab-on-papermilkcontamination
spellingShingle Hwee-Yeong Ng
Wen-Chin Lee
Chia-Te Kung
Lung-Chih Li
Chien-Te Lee
Lung-Ming Fu
Recent Advances in Microfluidic Devices for Contamination Detection and Quality Inspection of Milk
Micromachines
microfluidic
lab-on-a-chip
lab-on-paper
milk
contamination
title Recent Advances in Microfluidic Devices for Contamination Detection and Quality Inspection of Milk
title_full Recent Advances in Microfluidic Devices for Contamination Detection and Quality Inspection of Milk
title_fullStr Recent Advances in Microfluidic Devices for Contamination Detection and Quality Inspection of Milk
title_full_unstemmed Recent Advances in Microfluidic Devices for Contamination Detection and Quality Inspection of Milk
title_short Recent Advances in Microfluidic Devices for Contamination Detection and Quality Inspection of Milk
title_sort recent advances in microfluidic devices for contamination detection and quality inspection of milk
topic microfluidic
lab-on-a-chip
lab-on-paper
milk
contamination
url https://www.mdpi.com/2072-666X/12/5/558
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