Expanding the phenotypic spectrum of mutations in LRP2: a novel candidate gene of non-syndromic familial comitant strabismus

Expanding the phenotypic spectrum of mutations in LRP2: a novel candidate gene of non-syndromic familial comitant strabismus

Abstract Background Comitant strabismus (CS) is a heterogeneous disorder that is a major contributing factor to unilateral childhood-onset visual impairment. Studies have confirmed that genetic factors play an important role in the development of CS. The aim of this study was to identify the genetic...

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Bibliographic Details
Main Authors: Yue Wang, Xuejuan Chen, Tao Jiang, Yayun Gu, Xiaohan Zhang, Wenwen Yuan, Andi Zhao, Rui Li, Zijin Wang, Zhibin Hu, Hu Liu
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Journal of Translational Medicine
Subjects:
Comitant strabismus
Mutation
Phenotype
Whole-exome sequencing
Linkage analysis
Online Access:https://doi.org/10.1186/s12967-021-03155-z

Internet

https://doi.org/10.1186/s12967-021-03155-z

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