Prenatal SSRI Exposure Increases the Risk of Autism in Rodents via Aggravated Oxidative Stress and Neurochemical Changes in the Brain

Prenatal SSRI Exposure Increases the Risk of Autism in Rodents via Aggravated Oxidative Stress and Neurochemical Changes in the Brain

The mechanisms underlying selective serotonin reuptake inhibitor (SSRI) use during pregnancy as a major autism risk factor are unclear. Here, brain neurochemical changes following fluoxetine exposure and in an autism model were compared to determine the effects on autism risk. The study was performe...

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Bibliographic Details
Main Authors: Ramesa Shafi Bhat, Mona Alonazi, Sooad Al-Daihan, Afaf El-Ansary
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Metabolites
Subjects:
SSRI
autism
oxidative stress
neurotransmitters
fluoxetine
Online Access:https://www.mdpi.com/2218-1989/13/2/310

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