Ex vivo γH2AX assay for tumor radiosensitivity in primary prostate cancer patients and correlation with clinical parameters

Ex vivo γH2AX assay for tumor radiosensitivity in primary prostate cancer patients and correlation with clinical parameters

Abstract Backround Accurate surrogate parameters for radio resistance are warranted for individualized radiotherapy (RT) concepts in prostate cancer (PCa). The purpose of this study was to assess intertumoral heterogeneity in terms of radio resistance using an ex-vivo γH2AX assay after irradiation o...

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Bibliographic Details
Main Authors: Ioana M. Marinescu, Manuel Rogg, Simon Spohn, Moritz von Büren, Marius Kamps, Cordula A. Jilg, Elena Fountzila, Kyriaki Papadopoulou, Lara Ceci, Alisa Bettermann, Juri Ruf, Matthias Benndorf, Sonja Adebahr, Daniel Zips, Anca L. Grosu, Christoph Schell, Constantinos Zamboglou
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Radiation Oncology
Subjects:
Prostate cancer
Intrinsic radio sensitivity
γH2AX foci
Standardized uptake values
Radiotherapy
Online Access:https://doi.org/10.1186/s13014-022-02131-1

Internet

https://doi.org/10.1186/s13014-022-02131-1

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