Testis single-cell RNA-seq reveals the dynamics of de novo gene transcription and germline mutational bias in Drosophila

Testis single-cell RNA-seq reveals the dynamics of de novo gene transcription and germline mutational bias in Drosophila

The testis is a peculiar tissue in many respects. It shows patterns of rapid gene evolution and provides a hotspot for the origination of genetic novelties such as de novo genes, duplications and mutations. To investigate the expression patterns of genetic novelties across cell types, we performed s...

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Bibliographic Details
Main Authors: Evan Witt, Sigi Benjamin, Nicolas Svetec, Li Zhao
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-08-01
Series:eLife
Subjects:
de novo gene
mutational load
single-cell sequencing
expression dynamics
Drosophila
spermatogenesis
Online Access:https://elifesciences.org/articles/47138

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