Adverse effects of adjuvant endocrine therapy

Hormonal therapy is a highly effective and well tolerable treatment of hormone-responsive breast cancer. However, it has some side effects that can affect quality of life and lead to treatment discontinuation. Common side effects of tamoxifen and aromatase inhibitors are discussed in this article: m...

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Main Authors: E. I. Kovalenko, I. B. Kononenko, A. V. Snegovoi, O. P. Grebennikova, L. V. Manzyuk
Format: Article
Language:Russian
Published: Remedium Group LLC 2018-07-01
Series:Медицинский совет
Subjects:
Online Access:https://www.med-sovet.pro/jour/article/view/2534
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author E. I. Kovalenko
I. B. Kononenko
A. V. Snegovoi
O. P. Grebennikova
L. V. Manzyuk
author_facet E. I. Kovalenko
I. B. Kononenko
A. V. Snegovoi
O. P. Grebennikova
L. V. Manzyuk
author_sort E. I. Kovalenko
collection DOAJ
description Hormonal therapy is a highly effective and well tolerable treatment of hormone-responsive breast cancer. However, it has some side effects that can affect quality of life and lead to treatment discontinuation. Common side effects of tamoxifen and aromatase inhibitors are discussed in this article: menopausal, gynecological symptoms, cardiovascular and musculoskeletal adverse events. Some of them are preventable and manageable. In order to maintain good quality of life during treatment the oncologists should pay more attention to the side effects that lead to it’s deterioration and not be too anxious about insignificant ones.
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spelling doaj.art-33ce5c7e9a6b4da99c38b3622f483b172023-04-23T06:56:52ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902018-07-01010646910.21518/2079-701X-2018-10-64-692495Adverse effects of adjuvant endocrine therapyE. I. Kovalenko0I. B. Kononenko1A. V. Snegovoi2O. P. Grebennikova3L. V. Manzyuk4N.N.Blokhin Russian Cancer Research Centre of the Ministry of Health of RussiaN.N.Blokhin Russian Cancer Research Centre of the Ministry of Health of RussiaN.N.Blokhin Russian Cancer Research Centre of the Ministry of Health of RussiaA.I.Yevdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of RussiaN.N.Blokhin Russian Cancer Research Centre of the Ministry of Health of RussiaHormonal therapy is a highly effective and well tolerable treatment of hormone-responsive breast cancer. However, it has some side effects that can affect quality of life and lead to treatment discontinuation. Common side effects of tamoxifen and aromatase inhibitors are discussed in this article: menopausal, gynecological symptoms, cardiovascular and musculoskeletal adverse events. Some of them are preventable and manageable. In order to maintain good quality of life during treatment the oncologists should pay more attention to the side effects that lead to it’s deterioration and not be too anxious about insignificant ones.https://www.med-sovet.pro/jour/article/view/2534hormonal therapyside effectstamoxifenaromatase inhibitors
spellingShingle E. I. Kovalenko
I. B. Kononenko
A. V. Snegovoi
O. P. Grebennikova
L. V. Manzyuk
Adverse effects of adjuvant endocrine therapy
Медицинский совет
hormonal therapy
side effects
tamoxifen
aromatase inhibitors
title Adverse effects of adjuvant endocrine therapy
title_full Adverse effects of adjuvant endocrine therapy
title_fullStr Adverse effects of adjuvant endocrine therapy
title_full_unstemmed Adverse effects of adjuvant endocrine therapy
title_short Adverse effects of adjuvant endocrine therapy
title_sort adverse effects of adjuvant endocrine therapy
topic hormonal therapy
side effects
tamoxifen
aromatase inhibitors
url https://www.med-sovet.pro/jour/article/view/2534
work_keys_str_mv AT eikovalenko adverseeffectsofadjuvantendocrinetherapy
AT ibkononenko adverseeffectsofadjuvantendocrinetherapy
AT avsnegovoi adverseeffectsofadjuvantendocrinetherapy
AT opgrebennikova adverseeffectsofadjuvantendocrinetherapy
AT lvmanzyuk adverseeffectsofadjuvantendocrinetherapy