Vitamin D sufficiency enhances differentiation of patient-derived prostate epithelial organoids
Summary: Vitamin D is an essential steroid hormone that regulates systemic calcium homeostasis and cell fate decisions. The prostate gland is hormonally regulated, requiring steroids for proliferation and differentiation of secretory luminal cells. Vitamin D deficiency is associated with an increase...
Main Authors: | Tara McCray, Julian V. Pacheco, Candice C. Loitz, Jason Garcia, Bethany Baumann, Michael J. Schlicht, Klara Valyi-Nagy, Michael R. Abern, Larisa Nonn |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-01-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004220311718 |
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