Vitamin D sufficiency enhances differentiation of patient-derived prostate epithelial organoids

Summary: Vitamin D is an essential steroid hormone that regulates systemic calcium homeostasis and cell fate decisions. The prostate gland is hormonally regulated, requiring steroids for proliferation and differentiation of secretory luminal cells. Vitamin D deficiency is associated with an increase...

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Bibliographic Details
Main Authors: Tara McCray, Julian V. Pacheco, Candice C. Loitz, Jason Garcia, Bethany Baumann, Michael J. Schlicht, Klara Valyi-Nagy, Michael R. Abern, Larisa Nonn
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220311718

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