Evaluation of Vitamin D and Iron Status in Chronic Kidney Disease with Diabetes Mellitus Patients at a Tertiary Care Hospital
Introduction: Chronic kidney disease (CKD), caused by diabetes mellitus is common in India. There is alteration of vitamin D and iron in such conditions. The present study, was aimed to evaluate the level of vitamin D and iron in various stages of CKD to assist the understanding of these parameters...
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| Format: | Article |
| Language: | English |
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Sonali Sharma on behalf of Rajasthan University of Health Sciences
2023-12-01
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| Series: | RUHS Journal of Health Sciences |
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| Online Access: | https://ruhsjhs.in/articleDetails.php?artid=TWpZMg== |
| Summary: | Introduction: Chronic kidney disease (CKD), caused by diabetes mellitus is common in India. There is alteration of vitamin D and iron in such conditions. The present study, was aimed to evaluate the level of vitamin D and iron in various stages of CKD to assist the understanding of these parameters in the management of CKD. Methodology: A total of 140 newly diagnosed patients of CKD stage I to V, who were diabetic for at least 10 years and visiting the OPD of a tertiary care health care center over a period of one year were included in the study along with 60 non-CKD participants. The study included 60 type II diabetic patients without CKD. HbA1c, hemoglobin, serum iron, urine microalbumin, serum and urine creatinine, and serum vitamin D were measured for all study populations. Results: Hemoglobin (p value 0.04), iron (p value 0.02), eGFR (p value 0.04), vitamin D (p value 0.02), urine albumin (p value 0.0001), urine creatinine (p value 0.04), and ACR (p value 0.04) were significantly low in the CKD group as compared to non CKD group; except HbA1c (p value 0.02), which was higher in CKD group. Vitamin D and iron were found to be deficient in all stages of CKD, severity being observed more in later stages of disease. Conclusion: Screening for vitamin D and iron should be carried out for an optimal risk reduction strategy in all CKD patients with diabetes mellitus irrespective of its stages. |
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| ISSN: | 2456-8309 2582-3590 |