Evaluation of Vitamin D and Iron Status in Chronic Kidney Disease with Diabetes Mellitus Patients at a Tertiary Care Hospital
Introduction: Chronic kidney disease (CKD), caused by diabetes mellitus is common in India. There is alteration of vitamin D and iron in such conditions. The present study, was aimed to evaluate the level of vitamin D and iron in various stages of CKD to assist the understanding of these parameters...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sonali Sharma on behalf of Rajasthan University of Health Sciences
2023-12-01
|
| Series: | RUHS Journal of Health Sciences |
| Subjects: | |
| Online Access: | https://ruhsjhs.in/articleDetails.php?artid=TWpZMg== |
| _version_ | 1797371754598891520 |
|---|---|
| author | Mahammad Shaahid Mansuri, Bijali Chakrabarti, Chandan Chakrabarti |
| author_facet | Mahammad Shaahid Mansuri, Bijali Chakrabarti, Chandan Chakrabarti |
| author_sort | Mahammad Shaahid Mansuri, Bijali Chakrabarti, Chandan Chakrabarti |
| collection | DOAJ |
| description | Introduction: Chronic kidney disease (CKD), caused by diabetes mellitus is common in India. There is alteration of vitamin D and iron in such conditions. The present study, was aimed to evaluate the level of vitamin D and iron in various stages of CKD to assist the understanding of these parameters in the management of CKD. Methodology: A total of 140 newly diagnosed patients of CKD stage I to V, who were diabetic for at least 10 years and visiting the OPD of a tertiary care health care center over a period of one year were included in the study along with 60 non-CKD participants. The study included 60 type II diabetic patients without CKD. HbA1c, hemoglobin, serum iron, urine microalbumin, serum and urine creatinine, and serum vitamin D were measured for all study populations. Results: Hemoglobin (p value 0.04), iron (p value 0.02), eGFR (p value 0.04), vitamin D (p value 0.02), urine albumin (p value 0.0001), urine creatinine (p value 0.04), and ACR (p value 0.04) were significantly low in the CKD group as compared to non CKD group; except HbA1c (p value 0.02), which was higher in CKD group. Vitamin D and iron were found to be deficient in all stages of CKD, severity being observed more in later stages of disease. Conclusion: Screening for vitamin D and iron should be carried out for an optimal risk reduction strategy in all CKD patients with diabetes mellitus irrespective of its stages. |
| first_indexed | 2024-03-08T18:25:28Z |
| format | Article |
| id | doaj.art-33d0b417aaad45f0a44dcbd844214de0 |
| institution | Directory Open Access Journal |
| issn | 2456-8309 2582-3590 |
| language | English |
| last_indexed | 2024-03-08T18:25:28Z |
| publishDate | 2023-12-01 |
| publisher | Sonali Sharma on behalf of Rajasthan University of Health Sciences |
| record_format | Article |
| series | RUHS Journal of Health Sciences |
| spelling | doaj.art-33d0b417aaad45f0a44dcbd844214de02023-12-30T12:22:01ZengSonali Sharma on behalf of Rajasthan University of Health SciencesRUHS Journal of Health Sciences2456-83092582-35902023-12-01http://dx.doi.org/10.37821/ruhsjhs.8.4.2023.628Evaluation of Vitamin D and Iron Status in Chronic Kidney Disease with Diabetes Mellitus Patients at a Tertiary Care HospitalMahammad Shaahid Mansuri, Bijali Chakrabarti, Chandan Chakrabarti0Assistant Professor, Department of Biochemistry, Assistant Professor, Department of Pathology, Narendra Modi Medical College; Professor and Head, Department of Biochemistry, Smt NHL Municipal Medical College, Ahmedabad, Gujarat, IndiaIntroduction: Chronic kidney disease (CKD), caused by diabetes mellitus is common in India. There is alteration of vitamin D and iron in such conditions. The present study, was aimed to evaluate the level of vitamin D and iron in various stages of CKD to assist the understanding of these parameters in the management of CKD. Methodology: A total of 140 newly diagnosed patients of CKD stage I to V, who were diabetic for at least 10 years and visiting the OPD of a tertiary care health care center over a period of one year were included in the study along with 60 non-CKD participants. The study included 60 type II diabetic patients without CKD. HbA1c, hemoglobin, serum iron, urine microalbumin, serum and urine creatinine, and serum vitamin D were measured for all study populations. Results: Hemoglobin (p value 0.04), iron (p value 0.02), eGFR (p value 0.04), vitamin D (p value 0.02), urine albumin (p value 0.0001), urine creatinine (p value 0.04), and ACR (p value 0.04) were significantly low in the CKD group as compared to non CKD group; except HbA1c (p value 0.02), which was higher in CKD group. Vitamin D and iron were found to be deficient in all stages of CKD, severity being observed more in later stages of disease. Conclusion: Screening for vitamin D and iron should be carried out for an optimal risk reduction strategy in all CKD patients with diabetes mellitus irrespective of its stages.https://ruhsjhs.in/articleDetails.php?artid=TWpZMg==Chronic kidney disease, Diabetes mellitus, Iron, Vitamin D. |
| spellingShingle | Mahammad Shaahid Mansuri, Bijali Chakrabarti, Chandan Chakrabarti Evaluation of Vitamin D and Iron Status in Chronic Kidney Disease with Diabetes Mellitus Patients at a Tertiary Care Hospital RUHS Journal of Health Sciences Chronic kidney disease, Diabetes mellitus, Iron, Vitamin D. |
| title | Evaluation of Vitamin D and Iron Status in Chronic Kidney Disease with Diabetes Mellitus Patients at a Tertiary Care Hospital |
| title_full | Evaluation of Vitamin D and Iron Status in Chronic Kidney Disease with Diabetes Mellitus Patients at a Tertiary Care Hospital |
| title_fullStr | Evaluation of Vitamin D and Iron Status in Chronic Kidney Disease with Diabetes Mellitus Patients at a Tertiary Care Hospital |
| title_full_unstemmed | Evaluation of Vitamin D and Iron Status in Chronic Kidney Disease with Diabetes Mellitus Patients at a Tertiary Care Hospital |
| title_short | Evaluation of Vitamin D and Iron Status in Chronic Kidney Disease with Diabetes Mellitus Patients at a Tertiary Care Hospital |
| title_sort | evaluation of vitamin d and iron status in chronic kidney disease with diabetes mellitus patients at a tertiary care hospital |
| topic | Chronic kidney disease, Diabetes mellitus, Iron, Vitamin D. |
| url | https://ruhsjhs.in/articleDetails.php?artid=TWpZMg== |
| work_keys_str_mv | AT mahammadshaahidmansuribijalichakrabartichandanchakrabarti evaluationofvitamindandironstatusinchronickidneydiseasewithdiabetesmellituspatientsatatertiarycarehospital |