Regeneration of Hair Cells in the Human Vestibular System

The vestibular system is a critical part of the human balance system, malfunction of this system will lead to balance disorders, such as vertigo. Mammalian vestibular hair cells, the mechanical receptors for vestibular function, are sensitive to ototoxic drugs and virus infection, and have a limited...

全面介绍

书目详细资料
Main Authors: Yikang Huang, Huanyu Mao, Yan Chen
格式: 文件
语言:English
出版: Frontiers Media S.A. 2022-03-01
丛编:Frontiers in Molecular Neuroscience
主题:
在线阅读:https://www.frontiersin.org/articles/10.3389/fnmol.2022.854635/full
实物特征
总结:The vestibular system is a critical part of the human balance system, malfunction of this system will lead to balance disorders, such as vertigo. Mammalian vestibular hair cells, the mechanical receptors for vestibular function, are sensitive to ototoxic drugs and virus infection, and have a limited restorative capacity after damage. Considering that no artificial device can be used to replace vestibular hair cells, promoting vestibular hair cell regeneration is an ideal way for vestibular function recovery. In this manuscript, the development of human vestibular hair cells during the whole embryonic stage and the latest research on human vestibular hair cell regeneration is summarized. The limitations of current studies are emphasized and future directions are discussed.
ISSN:1662-5099