Management of a Young Patient With High-risk Multiple Myeloma Complicated by Acquired von Willebrand Syndrome: A Diagnostic and Therapeutic Emergency

Multiple myeloma associated with bleeding events secondary to von Willebrand syndrome is underdiagnosed. The management of this entity is highly complex, and aims to control the hemorrhagic syndrome and reduce plasma viscosity with plasmapheresis and multiple myeloma-specific treatment. The authors...

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Main Authors: Abakarim Ouadii MD, Condom Pauline MD, Voisin Sophie MD, Huart Antoine MD, Perrot Aurore PhD, Botin Teresa MD
Format: Article
Language:English
Published: SAGE Publishing 2024-01-01
Series:Plasmatology
Online Access:https://doi.org/10.1177/26348535231222994
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author Abakarim Ouadii MD
Condom Pauline MD
Voisin Sophie MD
Huart Antoine MD
Perrot Aurore PhD
Botin Teresa MD
author_facet Abakarim Ouadii MD
Condom Pauline MD
Voisin Sophie MD
Huart Antoine MD
Perrot Aurore PhD
Botin Teresa MD
author_sort Abakarim Ouadii MD
collection DOAJ
description Multiple myeloma associated with bleeding events secondary to von Willebrand syndrome is underdiagnosed. The management of this entity is highly complex, and aims to control the hemorrhagic syndrome and reduce plasma viscosity with plasmapheresis and multiple myeloma-specific treatment. The authors report the rare case of a young patient with high-risk multiple myeloma complicated by hyperviscosity syndrome and presenting an acquired von Willebrand syndrome with hemorrhagic manifestations, requiring urgent therapeutic management to save the patient's life.
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spelling doaj.art-33d3c5ef58a24c578ea9d8cfbe34360f2024-01-04T14:03:21ZengSAGE PublishingPlasmatology2634-85352024-01-011810.1177/26348535231222994Management of a Young Patient With High-risk Multiple Myeloma Complicated by Acquired von Willebrand Syndrome: A Diagnostic and Therapeutic EmergencyAbakarim Ouadii MD0Condom Pauline MD1Voisin Sophie MD2Huart Antoine MD3Perrot Aurore PhD4Botin Teresa MD5 Oncohematology Department, Castres-Mazamet Hospital, Faculty of Health, , France Medical biology Laboratory, Castres-Mazamet Hospital, Toulouse, France Hematology Laboratory, , Toulouse University Hospital, Toulouse, France Nephrology Department, , Toulouse University Hospital, Toulouse, France Hematology Department, , Toulouse University Hospital, Toulouse, France Oncohematology Department, Castres-Mazamet Hospital, Toulouse, FranceMultiple myeloma associated with bleeding events secondary to von Willebrand syndrome is underdiagnosed. The management of this entity is highly complex, and aims to control the hemorrhagic syndrome and reduce plasma viscosity with plasmapheresis and multiple myeloma-specific treatment. The authors report the rare case of a young patient with high-risk multiple myeloma complicated by hyperviscosity syndrome and presenting an acquired von Willebrand syndrome with hemorrhagic manifestations, requiring urgent therapeutic management to save the patient's life.https://doi.org/10.1177/26348535231222994
spellingShingle Abakarim Ouadii MD
Condom Pauline MD
Voisin Sophie MD
Huart Antoine MD
Perrot Aurore PhD
Botin Teresa MD
Management of a Young Patient With High-risk Multiple Myeloma Complicated by Acquired von Willebrand Syndrome: A Diagnostic and Therapeutic Emergency
Plasmatology
title Management of a Young Patient With High-risk Multiple Myeloma Complicated by Acquired von Willebrand Syndrome: A Diagnostic and Therapeutic Emergency
title_full Management of a Young Patient With High-risk Multiple Myeloma Complicated by Acquired von Willebrand Syndrome: A Diagnostic and Therapeutic Emergency
title_fullStr Management of a Young Patient With High-risk Multiple Myeloma Complicated by Acquired von Willebrand Syndrome: A Diagnostic and Therapeutic Emergency
title_full_unstemmed Management of a Young Patient With High-risk Multiple Myeloma Complicated by Acquired von Willebrand Syndrome: A Diagnostic and Therapeutic Emergency
title_short Management of a Young Patient With High-risk Multiple Myeloma Complicated by Acquired von Willebrand Syndrome: A Diagnostic and Therapeutic Emergency
title_sort management of a young patient with high risk multiple myeloma complicated by acquired von willebrand syndrome a diagnostic and therapeutic emergency
url https://doi.org/10.1177/26348535231222994
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