Electrochemical Sensing Platform Based on The Modified Carbon-Ceramic Electrode Using Multiwalled Carbon Nanotubes (MWCNTs) Through The Sol-Gel Process: Application in Sensitive Determination of Morin as A Common Flavonoids

Background: Morin is one of the most common flavonoids which found in nature, plantsand vegetable-derived foods and Brazilian yellow tree is a source for its extraction.Because of hydroxyl group existence, Morin represents better antioxidant properties andhave great significance in bio electrochemis...

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Main Authors: Sima Mehdipour, Mir Reza Majidi, Karim Asadpour-Zeynali, Hessamaddin Sohrabi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2022-06-01
Series:ImmunoAnalysis
Subjects:
Online Access:https://ia.tbzmed.ac.ir/PDF/ia-2-3.pdf
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author Sima Mehdipour
Mir Reza Majidi
Karim Asadpour-Zeynali
Hessamaddin Sohrabi
author_facet Sima Mehdipour
Mir Reza Majidi
Karim Asadpour-Zeynali
Hessamaddin Sohrabi
author_sort Sima Mehdipour
collection DOAJ
description Background: Morin is one of the most common flavonoids which found in nature, plantsand vegetable-derived foods and Brazilian yellow tree is a source for its extraction.Because of hydroxyl group existence, Morin represents better antioxidant properties andhave great significance in bio electrochemistry-based investigations. Methods: In this research work, an electrochemical-based sensing platform was designedbased on a modified carbon-ceramic electrode (CCE) through a sol-gel process withcarbon nanotubes for the investigation of the electrochemical behavior of Morin. Various electrochemical techniques have been used for the analytical investigation ofthe proposed sensing platform including cyclic voltammetry (CV), differential pulsevoltammetry (DPV), and anodic stripping voltammetry (ASV) methods. Furthermore, themorphological investigation was efficiently performed for the demonstration of electrodesurface characteristics. Results: The obtained results showed that the anodic peak currents increased linearly in aconcentration range of 0.7–3 μM, where detection limit is equal to 0.27 μM for DPV, andthe linear range is considered to be 0.6-4 μM where there is a lower detection limit of 0.3μM for ASV. Such a biosensing assay can also prove a great potential for the determinationof Morin in dry tea. Conclusion: As clearly demonstrated, Morin as one of the flavonoids which is a pentahydroxy flavone that is 7-hydroxy flavonol bearing three additional hydroxy substituents atpositions 2’ 4’ and 5. There are many conventional analytical methods for determinationof Morin. However, electrochemical-based sensing assay are cheaper, simpler and moreeconomical. Therefore, in this research work, we have used electrochemical-basedtechniques applying CCE modified MWCNTs and appropriate analytical features havebeen obtained.
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spelling doaj.art-33d95421ae9748839d8e6672e6296bd52023-05-29T05:14:26ZengTabriz University of Medical SciencesImmunoAnalysis2783-25892022-06-01213310.34172/ia.2022.03ia-3019Electrochemical Sensing Platform Based on The Modified Carbon-Ceramic Electrode Using Multiwalled Carbon Nanotubes (MWCNTs) Through The Sol-Gel Process: Application in Sensitive Determination of Morin as A Common FlavonoidsSima Mehdipour0Mir Reza Majidi1Karim Asadpour-Zeynali2Hessamaddin Sohrabi3Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz, IranDepartment of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz, IranDepartment of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz, IranDepartment of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz, IranBackground: Morin is one of the most common flavonoids which found in nature, plantsand vegetable-derived foods and Brazilian yellow tree is a source for its extraction.Because of hydroxyl group existence, Morin represents better antioxidant properties andhave great significance in bio electrochemistry-based investigations. Methods: In this research work, an electrochemical-based sensing platform was designedbased on a modified carbon-ceramic electrode (CCE) through a sol-gel process withcarbon nanotubes for the investigation of the electrochemical behavior of Morin. Various electrochemical techniques have been used for the analytical investigation ofthe proposed sensing platform including cyclic voltammetry (CV), differential pulsevoltammetry (DPV), and anodic stripping voltammetry (ASV) methods. Furthermore, themorphological investigation was efficiently performed for the demonstration of electrodesurface characteristics. Results: The obtained results showed that the anodic peak currents increased linearly in aconcentration range of 0.7–3 μM, where detection limit is equal to 0.27 μM for DPV, andthe linear range is considered to be 0.6-4 μM where there is a lower detection limit of 0.3μM for ASV. Such a biosensing assay can also prove a great potential for the determinationof Morin in dry tea. Conclusion: As clearly demonstrated, Morin as one of the flavonoids which is a pentahydroxy flavone that is 7-hydroxy flavonol bearing three additional hydroxy substituents atpositions 2’ 4’ and 5. There are many conventional analytical methods for determinationof Morin. However, electrochemical-based sensing assay are cheaper, simpler and moreeconomical. Therefore, in this research work, we have used electrochemical-basedtechniques applying CCE modified MWCNTs and appropriate analytical features havebeen obtained.https://ia.tbzmed.ac.ir/PDF/ia-2-3.pdfmorinmodified electrodecarbon nanotubescarbon ceramic electrodesol-gel process
spellingShingle Sima Mehdipour
Mir Reza Majidi
Karim Asadpour-Zeynali
Hessamaddin Sohrabi
Electrochemical Sensing Platform Based on The Modified Carbon-Ceramic Electrode Using Multiwalled Carbon Nanotubes (MWCNTs) Through The Sol-Gel Process: Application in Sensitive Determination of Morin as A Common Flavonoids
ImmunoAnalysis
morin
modified electrode
carbon nanotubes
carbon ceramic electrode
sol-gel process
title Electrochemical Sensing Platform Based on The Modified Carbon-Ceramic Electrode Using Multiwalled Carbon Nanotubes (MWCNTs) Through The Sol-Gel Process: Application in Sensitive Determination of Morin as A Common Flavonoids
title_full Electrochemical Sensing Platform Based on The Modified Carbon-Ceramic Electrode Using Multiwalled Carbon Nanotubes (MWCNTs) Through The Sol-Gel Process: Application in Sensitive Determination of Morin as A Common Flavonoids
title_fullStr Electrochemical Sensing Platform Based on The Modified Carbon-Ceramic Electrode Using Multiwalled Carbon Nanotubes (MWCNTs) Through The Sol-Gel Process: Application in Sensitive Determination of Morin as A Common Flavonoids
title_full_unstemmed Electrochemical Sensing Platform Based on The Modified Carbon-Ceramic Electrode Using Multiwalled Carbon Nanotubes (MWCNTs) Through The Sol-Gel Process: Application in Sensitive Determination of Morin as A Common Flavonoids
title_short Electrochemical Sensing Platform Based on The Modified Carbon-Ceramic Electrode Using Multiwalled Carbon Nanotubes (MWCNTs) Through The Sol-Gel Process: Application in Sensitive Determination of Morin as A Common Flavonoids
title_sort electrochemical sensing platform based on the modified carbon ceramic electrode using multiwalled carbon nanotubes mwcnts through the sol gel process application in sensitive determination of morin as a common flavonoids
topic morin
modified electrode
carbon nanotubes
carbon ceramic electrode
sol-gel process
url https://ia.tbzmed.ac.ir/PDF/ia-2-3.pdf
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AT mirrezamajidi electrochemicalsensingplatformbasedonthemodifiedcarbonceramicelectrodeusingmultiwalledcarbonnanotubesmwcntsthroughthesolgelprocessapplicationinsensitivedeterminationofmorinasacommonflavonoids
AT karimasadpourzeynali electrochemicalsensingplatformbasedonthemodifiedcarbonceramicelectrodeusingmultiwalledcarbonnanotubesmwcntsthroughthesolgelprocessapplicationinsensitivedeterminationofmorinasacommonflavonoids
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