Genetic and Chemical Capsid Modifications of Adenovirus Vectors to Modulate Vector–Host Interactions

Genetic and Chemical Capsid Modifications of Adenovirus Vectors to Modulate Vector–Host Interactions

Adenovirus-based vectors are playing an important role as efficacious genetic vaccines to fight the current COVID-19 pandemic. Furthermore, they have an enormous potential as oncolytic vectors for virotherapy and as vectors for classic gene therapy. However, numerous vector–host interactions on a ce...

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Bibliographic Details
Main Authors: Denice Weklak, Daniel Pembaur, Georgia Koukou, Franziska Jönsson, Claudia Hagedorn, Florian Kreppel
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Viruses
Subjects:
adenovirus
capsid modification
chemical modification
PEGylation
HPMA
COVID-19 vaccine
Online Access:https://www.mdpi.com/1999-4915/13/7/1300

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