Suppression of NANOG Expression Reduces Drug Resistance of Cancer Stem Cells in Glioblastoma

Suppression of NANOG Expression Reduces Drug Resistance of Cancer Stem Cells in Glioblastoma

Glioblastoma (GBM) is an aggressive and incurable primary brain tumor that harbors therapy-resistant cancer stem cells (CSCs). Due to the limited effectiveness of conventional chemotherapies and radiation treatments against CSCs, there is a critical need for the development of innovative therapeutic...

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Bibliographic Details
Main Authors: Jonhoi Smith, Melvin Field, Kiminobu Sugaya
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Genes
Subjects:
cancer stem cells
glioblastoma
stemness genes
NANOG
OCT4
RNAi
Online Access:https://www.mdpi.com/2073-4425/14/6/1276

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